Elevated concentration of homocysteine (Hcy) in the blood plasma, hyperhomocysteinemia
(HHcy), has been implicated in various disorders, including cardiovascular and …

Epidemiological studies established that elevated homocysteine, an important intermediate
in folate, vitamin B12, and one carbon metabolism, is associated with poor health, including …

The primary goals of this study were to evaluate the gender-and age-related differences in
homocysteine concentration in the general population of China and possible influencing …

Cytochrome c (cyt c) is an electron transporter of the mitochondrial respiratory chain. Upon
permeabilization of the mitochondrial outer membrane, cyt c is released into the cytoplasm …

Accumulating evidence suggests that homocysteine (Hcy) metabolite, the thioester Hcy-
thiolactone, plays an important role in atherothrombosis. Hcy-thiolactone is a product of an …

Elevated levels of homocysteine are associated with several major diseases. However, it is
not clear whether homocysteine is a marker or a causative agent. The majority (ca. 80%) of …

Homocysteine (Hcy) is an accepted independent risk factor for several major pathologies
including cardiovascular disease, birth defects, osteoporosis, Alzheimer's disease, and renal …

Abstract Background Homocysteine (Hcy) is a sulfur containing non-protein amino acid that
occupies a central role in metabolism of thiol compounds. The past decade had noticed an …

Mitochondria are the powerhouses of the cell, whilst their malfunction is related to several
human pathologies, including neurodegenerative diseases, cardiovascular diseases, and …

Both epidemiological and experimental studies suggest that exposure to high levels of air
pollution is a risk factor associated with cardiovascular disease. Traffic emission is a major …