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Tumour-associated mesenchymal stem/stromal cells: emerging therapeutic targets
Mesenchymal stem cells, also known as mesenchymal stromal cells (MSCs), exist in many
tissues and are known to actively migrate to sites of tissue injury, where they participate in …
tissues and are known to actively migrate to sites of tissue injury, where they participate in …
[HTML][HTML] Mesenchymal stem cell-derived exosome: A tumor regulator and carrier for targeted tumor therapy
F Zhang, J Guo, Z Zhang, Y Qian, G Wang, M Duan… - Cancer letters, 2022 - Elsevier
Mesenchymal stem cells (MSCs) are multipotent stromal cells that have the ability to
differentiate into multiple cell types. Several studies have shown that exosomes secreted by …
differentiate into multiple cell types. Several studies have shown that exosomes secreted by …
Targeted exosome‐encapsulated erastin induced ferroptosis in triple negative breast cancer cells
Ferroptosis is an iron‐dependent, lipid peroxide‐driven cell death caused by inhibition of the
cystine/glutamate transporter, which is of importance for the survival of triple‐negative breast …
cystine/glutamate transporter, which is of importance for the survival of triple‐negative breast …
Tumor-associated macrophages-derived exosomes promote the migration of gastric cancer cells by transfer of functional Apolipoprotein E
P Zheng, Q Luo, W Wang, J Li, T Wang, P Wang… - Cell death & …, 2018 - nature.com
Tumor-associated macrophages (TAMs) are a major component of the tumor
microenvironment and have been shown to contribute to tumor aggressiveness. However …
microenvironment and have been shown to contribute to tumor aggressiveness. However …
M1-like tumor-associated macrophages activated by exosome-transferred THBS1 promote malignant migration in oral squamous cell carcinoma
Background Treatment strategies targeting tumor-associated macrophages (TAMs) have
been proposed in cancer areas. The functional alterations of macrophages in the …
been proposed in cancer areas. The functional alterations of macrophages in the …
SALL4-mediated upregulation of exosomal miR-146a-5p drives T-cell exhaustion by M2 tumor-associated macrophages in HCC
C Yin, Q Han, D Xu, B Zheng, X Zhao, J Zhang - Oncoimmunology, 2019 - Taylor & Francis
Emerging evidence indicates that cancer cell-derived exosomes contribute to cancer
progression through the modulation of tumor microenvironment, but the underlying …
progression through the modulation of tumor microenvironment, but the underlying …
Microvesicles and chemokines in tumor microenvironment: mediators of intercellular communications in tumor progression
Increasing evidence indicates that the ability of cancer cells to convey biological information
to recipient cells within the tumor microenvironment (TME) is crucial for tumor progression …
to recipient cells within the tumor microenvironment (TME) is crucial for tumor progression …
The cancer exosomes: Clinical implications, applications and challenges
The exosome is a small functional vesicle enriched in selected proteins, lipids and nucleic
acids, displaying distinct molecular heterogeneity. Exosomes released can transform the …
acids, displaying distinct molecular heterogeneity. Exosomes released can transform the …
Crucial biological functions of CCL7 in cancer
Y Liu, Y Cai, L Liu, Y Wu, X **ong - PeerJ, 2018 - peerj.com
Abstract Chemokine (CC motif) ligand 7 (CCL7), a CC chemokine, is a chemotactic factor
and attractant for various kinds of leukocytes, including monocytes and neutrophils. CCL7 is …
and attractant for various kinds of leukocytes, including monocytes and neutrophils. CCL7 is …
[HTML][HTML] The role of secreted factors in stem cells-mediated immune regulation
Stem cells are characterized by self-renew and multipotent differentiation abilities. Besides
their roles in cell compensation, stem cells are also rich sources of growth factors, cytokines …
their roles in cell compensation, stem cells are also rich sources of growth factors, cytokines …