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The concept of central nervous system (CNS) inflammation has evolved over the last
decades. Neuroinflammation is the response of reactive CNS components to altered …

Hypoxia and inflammation are frequently co-incidental features of the tissue
microenvironment in a wide range of inflammatory diseases. While the impact of hypoxia on …

This review deals with emerging evidence of an association between systemic or local
hypoxia and inflammation in a variety of diseases. The evidence points to new ways of …

This review provides an overview of the relationship between ventilation/perfusion ratios
and gas exchange in the lung, emphasising basic concepts and relating them to clinical …

Acute hypobaric hypoxia (HH) is a major physiological threat during high-altitude flight and
operations. In military aviation, although hypoxia-related fatalities are rare, incidences are …

Hypoxia-inducible factors (HIFs) are stabilized during adverse inflammatory processes
associated with disorders such as inflammatory bowel disease, pathogen infection and …

Normal birth is a eustress reaction, a beneficial hedonic stress with extremely high
catecholamines that protects us from intrauterine hypoxia and assists in the rapid shift to …

The Himalayan Sherpas, a human population of Tibetan descent, are highly adapted to life
in the hypobaric hypoxia of high altitude. Mechanisms involving enhanced tissue oxygen …

The human body is a highly aerobic organism, in which it is necessary to match oxygen
supply at tissue levels to the metabolic demands. Along metazoan evolution, an exquisite …