Simple Summary Fluid-structure interaction algorithms are utilized to examine how the
human circulatory system functions by simulating blood flow and capturing mechanical …

This paper provides a review of engineering applications and computational methods used
to analyze the dynamics of heart valve closures in healthy and diseased states …

Computational modeling of heart valve dynamics incorporating both fluid dynamics and
valve structural responses has been challenging. In this study, we developed a novel fully …

Cardiovascular malformations and diseases are common but complex and often not yet fully
understood. To better understand the effects of structural and microstructural changes of the …

Simple Summary Computational simulations of biological systems are an intrinsic element of
engineering in medicine, allowing physicians the ability to visualize the pathophysiology …

Patient-specific simulation of the fluid–structure interaction (FSI) problems in cardiovascular
systems plays an increasingly important role in fundamental research and clinical …

Proper tricuspid valve (TV) function is essential to unidirectional blood flow through the right
side of the heart. Alterations to the tricuspid valvular components, such as the TV annulus …

Computational modeling can be used to improve understanding of tricuspid valve (TV)
biomechanics and supplement knowledge gained from benchtop and large animal …

Over the years, three‐dimensional models of the mitral valve have generally been organized
around a simplified anatomy. Leaflets have been typically modeled as membranes, tethered …

Computational modeling of the mitral valve (MV) has potential applications for determining
optimal MV repair techniques and risk of recurrent mitral regurgitation. Two key concerns for …