Liquid biopsies are increasingly used for cancer molecular profiling that enables a precision
oncology approach. Circulating extracellular nucleic acids (cell-free DNA; cfDNA) …

Circulating tumor cells (CTCs) are tumor cells that have sloughed off the primary tumor and
extravasate into and circulate in the blood. Understanding of the metastatic cascade of CTCs …

The importance of early cancer diagnosis and improved cancer therapy has been clear for
years and has initiated worldwide research towards new possibilities in the care strategy of …

Circulating tumor cells, a component of the “liquid biopsy”, hold great potential to transform
the current landscape of cancer therapy. A key challenge to unlocking the clinical utility of …

Circulating tumor cells (CTCs) are rare cancer cells that are shed from primary or metastatic
tumors into the peripheral blood circulation. Phenotypic and genetic characterization of …

Epithelial-mesenchymal transition (EMT) of adherent epithelial cells to a migratory
mesenchymal state has been implicated in tumor metastasis in preclinical models. To …

The ability to isolate and analyze rare circulating tumor cells (CTCs) has the potential to
further our understanding of cancer metastasis and enhance the care of cancer patients. In …

BACKGROUND The detection and molecular characterization of circulating tumor cells
(CTCs) are one of the most active areas of translational cancer research, with> 400 clinical …

Presence and frequency of rare circulating tumor cells (CTCs) in bloodstreams of cancer
patients are pivotal to early cancer detection and treatment monitoring. Here, we use a spiral …

Ovarian cancer is the most lethal gynecological malignancy. It is usually diagnosed at a late
stage, with a 5-yr survival rate of< 30%. The majority of ovarian cancer cases are diagnosed …