MicroRNAs in cancer—from research to therapy
WCS Cho - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2010 - Elsevier
MicroRNAs (miRNAs) regulate target gene expression through translation repression or
mRNA degradation. These non-coding RNAs are emerging as important modulators in …
mRNA degradation. These non-coding RNAs are emerging as important modulators in …
Micro RNA‐145: a potent tumour suppressor that regulates multiple cellular pathways
SY Cui, R Wang, LB Chen - Journal of cellular and molecular …, 2014 - Wiley Online Library
Micro RNA s are endogenous, small (18–25 nucleotides) non‐coding RNA s, which regulate
genes expression by directly binding to the 3′‐untranslated regions of the target …
genes expression by directly binding to the 3′‐untranslated regions of the target …
MicroRNA-31 functions as an oncogenic microRNA in mouse and human lung cancer cells by repressing specific tumor suppressors
X Liu, LF Sempere, H Ouyang… - The Journal of …, 2010 - Am Soc Clin Investig
MicroRNAs (miRNAs) regulate gene expression. It has been suggested that obtaining
miRNA expression profiles can improve classification, diagnostic, and prognostic …
miRNA expression profiles can improve classification, diagnostic, and prognostic …
MicroRNA expression differentiates histology and predicts survival of lung cancer
Purpose: The molecular drivers that determine histology in lung cancer are largely unknown.
We investigated whether microRNA (miR) expression profiles can differentiate histologic …
We investigated whether microRNA (miR) expression profiles can differentiate histologic …
miR-145 and miR-133a function as tumour suppressors and directly regulate FSCN1 expression in bladder cancer
T Chiyomaru, H Enokida, S Tatarano… - British journal of …, 2010 - nature.com
Background: We have recently identified down-regulated microRNAs including miR-145 and
miR-133a in bladder cancer (BC). The aim of this study is to determine the genes targeted …
miR-133a in bladder cancer (BC). The aim of this study is to determine the genes targeted …
MiR-145 directly targets p70S6K1 in cancer cells to inhibit tumor growth and angiogenesis
Q Xu, LZ Liu, X Qian, Q Chen, Y Jiang, D Li… - Nucleic acids …, 2012 - academic.oup.com
MiR-145 can regulate cell apoptosis, proliferation, neural development and stem cell
differentiation. Previous studies indicate that miR-145 is downregulated in human colon …
differentiation. Previous studies indicate that miR-145 is downregulated in human colon …
Green tea polyphenol EGCG suppresses lung cancer cell growth through upregulating miR-210 expression caused by stabilizing HIF-1α
H Wang, S Bian, CS Yang - Carcinogenesis, 2011 - academic.oup.com
Epigallocatechin-3-gallate (EGCG) has been reported to affect many cellular regulatory
pathways. This study aims to determine whether EGCG could target microRNA (miRNA) …
pathways. This study aims to determine whether EGCG could target microRNA (miRNA) …
Identification of miRs-143 and-145 that is associated with bone metastasis of prostate cancer and involved in the regulation of EMT
X Peng, W Guo, T Liu, X Wang, X Tu, D **ong, S Chen… - PloS one, 2011 - journals.plos.org
The principal problem arising from prostate cancer (PCa) is its propensity to metastasize to
bone. MicroRNAs (miRNAs) play a crucial role in many tumor metastases. The importance of …
bone. MicroRNAs (miRNAs) play a crucial role in many tumor metastases. The importance of …
miR-145-dependent targeting of junctional adhesion molecule A and modulation of fascin expression are associated with reduced breast cancer cell motility and …
Micro RNAs are small non-coding RNAs, which regulate fundamental cellular and
developmental processes at the transcriptional and translational level. In breast cancer, miR …
developmental processes at the transcriptional and translational level. In breast cancer, miR …
miR-143 is downregulated in cervical cancer and promotes apoptosis and inhibits tumor formation by targeting Bcl-2
Abstract microRNAs (miRNAs) are small non-coding RNA molecules of 21-24 nt that
regulate the expression of other genes by transcriptional inhibition or translational …
regulate the expression of other genes by transcriptional inhibition or translational …