Immune activation, inflammation, and non-AIDS co-morbidities in HIV-infected patients under long-term ART

S Zicari, L Sessa, N Cotugno, A Ruggiero, E Morrocchi… - Viruses, 2019 - mdpi.com
Despite effective antiretroviral therapy (ART), people living with HIV (PLWH) still present
persistent chronic immune activation and inflammation. This condition is the result of several …

Advanced liposome-loaded scaffolds for therapeutic and tissue engineering applications

R Cheng, L Liu, Y **ang, Y Lu, L Deng, H Zhang… - Biomaterials, 2020 - Elsevier
Liposome is one of the most commonly used drug delivery systems in the world, due to its
excellent biocompatibility, satisfactory ability in controlling drug release, and passive …

Dolutegravir plus two different prodrugs of tenofovir to treat HIV

WDF Venter, M Moorhouse, S Sokhela… - … England Journal of …, 2019 - Mass Medical Soc
Background Two drugs under consideration for inclusion in antiretroviral therapy (ART)
regimens for human immunodeficiency virus (HIV) infection are dolutegravir (DTG) and …

HIV and cardiovascular disease

K So-Armah, LA Benjamin, GS Bloomfield… - The lancet HIV, 2020 - thelancet.com
HIV-related cardiovascular disease research is predominantly from Europe and North
America. Of the estimated 37· 9 million people living with HIV worldwide, 25· 6 million live in …

Pathogenesis of HIV-related lung disease: immunity, infection, and inflammation

SK Cribbs, K Crothers, A Morris - Physiological reviews, 2020 - journals.physiology.org
Despite anti-retroviral therapy (ART), human immunodeficiency virus-1 (HIV)-related
pulmonary disease continues to be a major cause of morbidity and mortality for people living …

Strategies to optimize the efficacy of anthelmintic drugs in ruminants

C Lanusse, C Canton, G Virkel, L Alvarez… - Trends in …, 2018 - cell.com
Anthelmintic resistance in human and animal pathogenic helminths has been spreading in
prevalence and severity. Multidrug resistance is a widespread problem in livestock animals …

Rapid initiation of antiretroviral therapy at HIV diagnosis: definition, process, knowledge gaps

MA Boyd, M Boffito, A Castagna, V Estrada - HIV medicine, 2019 - Wiley Online Library
Initiating antiretroviral therapy (ART) as early as the day of HIV diagnosis is a strategy of
increasing global interest to control the HIV epidemic and optimize the health of people …

HIV proteins and endothelial dysfunction: implications in cardiovascular disease

AR Anand, G Rachel, D Parthasarathy - Frontiers in cardiovascular …, 2018 - frontiersin.org
With the success of antiretroviral therapy (ART), a dramatic decrease in viral burden and
opportunistic infections and an increase in life expectancy has been observed in human …

A review of non-alcoholic fatty liver disease in HIV-infected patients: the next big thing?

BJ van Welzen, T Mudrikova, A El Idrissi… - Infectious diseases and …, 2019 - Springer
The burden of liver-related morbidity remains high among HIV-infected patients, despite
advances in the treatment of HIV and viral hepatitis. Especially, the impact of non-alcoholic …

Two‐drug vs. three‐drug combinations for HIV‐1: Do we have enough data to make the switch?

S Moreno, CF Perno, PW Mallon, G Behrens… - HIV …, 2019 - Wiley Online Library
Three‐drug combination antiretroviral therapy (ART) became available in 1996, dramatically
improving the prognosis of people living with HIV. The clinical benefits of ART are due to the …