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[HTML][HTML] Sustained and targeted delivery of hydrophilic drug compounds: A review of existing and novel technologies from bench to bedside
The sustained and/or targeted delivery of hydrophilic drugs is an important field within drug
delivery, presenting unique challenges when compared to that of hydrophobic drugs. Yet …
delivery, presenting unique challenges when compared to that of hydrophobic drugs. Yet …
Recent advances and prospects in gemcitabine drug delivery systems
Cancer is a community health hazard which progress at a fatal rate in various countries
across the globe. An agent used for chemotherapy should exhibit ideal properties to be an …
across the globe. An agent used for chemotherapy should exhibit ideal properties to be an …
Molecular polymer bottlebrushes in nanomedicine: therapeutic and diagnostic applications
Molecular polymer bottlebrushes are densely grafted, individual macromolecules with
nanoscale proportions. The last decade has seen an increased focus on this material class …
nanoscale proportions. The last decade has seen an increased focus on this material class …
Recent advances in formulation and application of molecular polymer brushes in biomedicine: Therapeutic, diagnostic, and theranostics capabilities
The applications of nanotechnology in medical sciences, especially in drug and gene
delivery, has experienced unprecedented growth in recent years. The integration of …
delivery, has experienced unprecedented growth in recent years. The integration of …
Therapeutic and responsive release mechanisms of polymer drug conjugates with diverse polymer skeletons
W Zhao, K Sun, J Yan, Y Sun, D Wei - Nano Today, 2024 - Elsevier
Polymer-drug conjugates (PDCs) have emerged as an advanced strategy in the drug
delivery. The conjugation of therapeutic or diagnostic agents to polymers, such as …
delivery. The conjugation of therapeutic or diagnostic agents to polymers, such as …
Biodegradable zwitterionic polymers as PEG alternatives for drug delivery
Abstract Poly (ethylene glycol)(PEG) is a highly biocompatible and water‐soluble polymer
that is widely utilized for biomedical applications. Unfortunately, the immunogenicity and …
that is widely utilized for biomedical applications. Unfortunately, the immunogenicity and …
Self-assembly of a linear–dendritic polymer containing cisplatin and norcantharidin into raspberry-like multimicelle clusters for the efficient chemotherapy of liver …
M Wei, Y Jiang, R Sun, L Fang, C Chu… - … Applied Materials & …, 2023 - ACS Publications
Combination chemotherapy has been proved to be an effective strategy in the clinic, and
nanoformulations have drawn much attention in the field of drug delivery. However …
nanoformulations have drawn much attention in the field of drug delivery. However …
A sulfobetaine zwitterionic polymer–drug conjugate for multivalent paclitaxel and gemcitabine co-delivery
A zwitterionic polymer–drug conjugate (ZPDC) strategy is developed for the co-delivery of
paclitaxel (PTX) and gemcitabine (GEM) chemotherapeutics, as well as a near-infrared …
paclitaxel (PTX) and gemcitabine (GEM) chemotherapeutics, as well as a near-infrared …
Characterization and preliminary in vitro antioxidant activity of a new multidrug formulation based on the co-encapsulation of rutin and the α-acylamino-β-lactone …
A biodegradable and biocompatible polymeric matrix made up of poly (d, l-lactide-co-
glycolide)(PLGA) was used for the simultaneous delivery of rutin and the (S)-N-(2-oxo-3 …
glycolide)(PLGA) was used for the simultaneous delivery of rutin and the (S)-N-(2-oxo-3 …
A tale of drug-carrier optimization: controlling stimuli sensitivity via nanoparticle hydrophobicity through drug loading
Interactions between drug molecules, nanocarrier components, and surrounding media
influence the properties and therapeutic efficacies of nanomedicines. In this study, we …
influence the properties and therapeutic efficacies of nanomedicines. In this study, we …