[HTML][HTML] Colonic drug delivery: Formulating the next generation of colon-targeted therapeutics

LE McCoubrey, A Favaron, A Awad, M Orlu… - Journal of Controlled …, 2023 - Elsevier
Colonic drug delivery can facilitate access to unique therapeutic targets and has the
potential to enhance drug bioavailability whilst reducing off-target effects. Delivering drugs to …

Machine learning directed drug formulation development

P Bannigan, M Aldeghi, Z Bao, F Häse… - Advanced Drug Delivery …, 2021 - Elsevier
Abstract Machine learning (ML) has enabled ground-breaking advances in the healthcare
and pharmaceutical sectors, from improvements in cancer diagnosis, to the identification of …

Machine learning models to accelerate the design of polymeric long-acting injectables

P Bannigan, Z Bao, RJ Hickman, M Aldeghi… - Nature …, 2023 - nature.com
Long-acting injectables are considered one of the most promising therapeutic strategies for
the treatment of chronic diseases as they can afford improved therapeutic efficacy, safety …

[HTML][HTML] Simulation-based approaches for drug delivery systems: Navigating advancements, opportunities, and challenges

I Salahshoori, M Golriz, MAL Nobre, S Mahdavi… - Journal of Molecular …, 2024 - Elsevier
Efficient drug delivery systems (DDSs) play a pivotal role in ensuring pharmaceuticals'
targeted and effective administration. However, the intricate interplay between drug …

An in silico study of sustainable drug pollutants removal using carboxylic acid functionalized-MOF nanostructures (MIL-53 (Al)-(COOH) 2): Towards a greener future

I Salahshoori, MN Jorabchi, S Ghasemi, M Golriz… - Desalination, 2023 - Elsevier
Emerging environmental pollutants have become a major environmental challenge due to
the highly toxic effluents produced by industries. Among these emerging pollutants …

How can machine learning and multiscale modeling benefit ocular drug development?

N Wang, Y Zhang, W Wang, Z Ye, H Chen, G Hu… - Advanced Drug Delivery …, 2023 - Elsevier
The eyes possess sophisticated physiological structures, diverse disease targets, limited
drug delivery space, distinctive barriers, and complicated biomechanical processes …

[HTML][HTML] Computer-aided nanodrug discovery: recent progress and future prospects

JJ Zheng, QZ Li, Z Wang, X Wang, Y Zhao… - Chemical Society …, 2024 - pubs.rsc.org
Nanodrugs, which utilise nanomaterials in disease prevention and therapy, have attracted
considerable interest since their initial conceptualisation in the 1990s. Substantial efforts …

Peptide-based drug delivery systems

D Berillo, A Yeskendir, Z Zharkinbekov, K Raziyeva… - Medicina, 2021 - mdpi.com
Peptide-based drug delivery systems have many advantages when compared to synthetic
systems in that they have better biocompatibility, biochemical and biophysical properties …

Surface functionalization of graphene‐based materials: Biological behavior, toxicology, and safe‐by‐design aspects

Z Guo, S Chakraborty, FA Monikh, DD Varsou… - Advanced …, 2021 - Wiley Online Library
The increasing exploitation of graphene‐based materials (GBMs) is driven by their unique
properties and structures, which ignite the imagination of scientists and engineers. At the …

[HTML][HTML] Advancements in molecular simulation for understanding pharmaceutical pollutant Adsorption: A State-of-the-Art review

I Salahshoori, S Mahdavi, Z Moradi, M Otadi… - Journal of Molecular …, 2024 - Elsevier
The contamination of natural water resources by pharmaceutical pollutants has become a
significant environmental concern. Traditional experimental approaches for understanding …