Interpreting the genomic landscape of speciation: a road map for finding barriers to gene flow

M Ravinet, R Faria, RK Butlin, J Galindo… - Journal of …, 2017 - academic.oup.com
Speciation, the evolution of reproductive isolation among populations, is continuous,
complex, and involves multiple, interacting barriers. Until it is complete, the effects of this …

Sex chromosome evolution: so many exceptions to the rules

BLS Furman, DCH Metzger, I Darolti… - Genome biology and …, 2020 - academic.oup.com
Genomic analysis of many nonmodel species has uncovered an incredible diversity of sex
chromosome systems, making it possible to empirically test the rich body of evolutionary …

Understanding the genetic basis of variation in meiotic recombination: past, present, and future

SE Johnston - Molecular Biology and Evolution, 2024 - academic.oup.com
Meiotic recombination is a fundamental feature of sexually reproducing species. It is often
required for proper chromosome segregation and plays important role in adaptation and the …

Characterizing mutagenic effects of recombination through a sequence-level genetic map

BV Halldorsson, G Palsson, OA Stefansson, H Jonsson… - Science, 2019 - science.org
INTRODUCTION Diversity in the sequence of the human genome, arising from
recombinations and mutations, is fundamental to human evolution and human diversity …

A map of human genome variation from population scale sequencing

1000 Genomes Project Consortium - Nature, 2010 - pmc.ncbi.nlm.nih.gov
The 1000 Genomes Project aims to provide a deep characterisation of human genome
sequence variation as a foundation for investigating the relationship between genotype and …

Meiotic DNA breaks drive multifaceted mutagenesis in the human germ line

R Hinch, P Donnelly, AG Hinch - Science, 2023 - science.org
Meiotic recombination commences with hundreds of programmed DNA breaks; however, the
degree to which they are accurately repaired remains poorly understood. We report that …

Meiotic recombination in mammals: localization and regulation

F Baudat, Y Imai, B De Massy - Nature Reviews Genetics, 2013 - nature.com
During meiosis, a programmed induction of DNA double-strand breaks (DSBs) leads to the
exchange of genetic material between homologous chromosomes. These exchanges …

Take a walk on the KRAB side

O Rosspopoff, D Trono - Trends in Genetics, 2023 - cell.com
Canonical Krüppel-associated box (KRAB)-containing zinc finger proteins (KZFPs) act as
major repressors of transposable elements (TEs) via the KRAB-mediated recruitment of the …

Mechanism and regulation of meiotic recombination initiation

I Lam, S Keeney - Cold Spring Harbor perspectives in …, 2015 - cshperspectives.cshlp.org
Meiotic recombination involves the formation and repair of programmed DNA double-strand
breaks (DSBs) catalyzed by the conserved Spo11 protein. This review summarizes recent …

[책][B] The evolution of sex determination

LW Beukeboom, N Perrin - 2014 - books.google.com
Sexual reproduction is a fundamental aspect of life. It is defined by the occurrence of meiosis
and the fusion of two gametes of different sexes or mating types. Sex-determination …