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Perspectives on the Drosophila melanogaster Model for Advances in Toxicological Science
MD Rand, JM Tennessen, TFC Mackay… - Current …, 2023 - Wiley Online Library
The use of Drosophila melanogaster for studies of toxicology has grown considerably in the
last decade. The Drosophila model has long been appreciated as a versatile and powerful …
last decade. The Drosophila model has long been appreciated as a versatile and powerful …
Heavy metal exposure and metabolomics analysis: an emerging frontier in environmental health
Exposure to heavy metals in various populations can lead to extensive damage to different
organs, as these metals infiltrate and bioaccumulate in the human body, causing metabolic …
organs, as these metals infiltrate and bioaccumulate in the human body, causing metabolic …
Molecular mechanisms of temperature tolerance plasticity in an arthropod
How species thrive in a wide range of environments is a major focus of evolutionary biology.
For many species, limited genetic diversity or gene flow among habitats means that …
For many species, limited genetic diversity or gene flow among habitats means that …
Rapid Adjustments in Thermal Tolerance and the Metabolome to Daily Environmental Changes – A Field Study on the Arctic Seed Bug Nysius groenlandicus
Laboratory investigations on terrestrial model-species, typically of temperate origin, have
demonstrated that terrestrial ectotherms can cope with daily temperature variations through …
demonstrated that terrestrial ectotherms can cope with daily temperature variations through …
Improving genomic prediction for seed quality traits in oat (Avena sativa L.) using trait-specific relationship matrices
The observable phenotype is the manifestation of information that is passed along different
organization levels (transcriptional, translational, and metabolic) of a biological system. The …
organization levels (transcriptional, translational, and metabolic) of a biological system. The …
Leveraging Multiple Layers of Data To Predict Drosophila Complex Traits
The ability to accurately predict complex trait phenotypes from genetic and genomic data are
critical for the implementation of personalized medicine and precision agriculture; however …
critical for the implementation of personalized medicine and precision agriculture; however …
A Drosophila melanogaster model for TMEM43-related arrhythmogenic right ventricular cardiomyopathy type 5
N Klinke, H Meyer, S Ratnavadivel, M Reinhardt… - Cellular and Molecular …, 2022 - Springer
Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a severe cardiac disease that
leads to heart failure or sudden cardiac death (SCD). For the pathogenesis of ARVC, various …
leads to heart failure or sudden cardiac death (SCD). For the pathogenesis of ARVC, various …
Comparing statistical learning methods for complex trait prediction from gene expression
N Klimkowski Arango, F Morgante - PloS one, 2025 - journals.plos.org
Accurate prediction of complex traits is an important task in quantitative genetics. Genotypes
have been used for trait prediction using a variety of methods such as mixed models …
have been used for trait prediction using a variety of methods such as mixed models …
Metabolomic spectra for phenotypic prediction of malting quality in spring barley
We investigated prediction of malting quality (MQ) phenotypes in different locations using
metabolomic spectra, and compared the prediction ability of different models, and training …
metabolomic spectra, and compared the prediction ability of different models, and training …
Multi-omics to predict changes during cold pressor test
Background The cold pressor test (CPT) is a widely used pain provocation test to investigate
both pain tolerance and cardiovascular responses. We hypothesize, that performing multi …
both pain tolerance and cardiovascular responses. We hypothesize, that performing multi …