Re-examining the Mysterious Role of the Cerebellum in Pain
Pain is considered a multidimensional experience that embodies not merely sensation, but
also emotion and perception. As is appropriate for this complexity, pain is represented and …
also emotion and perception. As is appropriate for this complexity, pain is represented and …
Cognitive-affective functions of the cerebellum
The cerebellum, traditionally associated with motor coordination and balance, also plays a
crucial role in various aspects of higher-order function and dysfunction. Emerging research …
crucial role in various aspects of higher-order function and dysfunction. Emerging research …
Memory trace for fear extinction: fragile yet reinforceable
Y Liu, S Ye, XN Li, WG Li - Neuroscience Bulletin, 2024 - Springer
Fear extinction is a biological process in which learned fear behavior diminishes without
anticipated reinforcement, allowing the organism to re-adapt to ever-changing situations …
anticipated reinforcement, allowing the organism to re-adapt to ever-changing situations …
A Purkinje cell to parabrachial nucleus pathway enables broad cerebellar influence over the forebrain
In addition to its motor functions, the cerebellum is involved in emotional regulation, anxiety
and affect. We found that suppressing the firing of cerebellar Purkinje cells (PCs) rapidly …
and affect. We found that suppressing the firing of cerebellar Purkinje cells (PCs) rapidly …
Cerebellar control of fear learning via the cerebellar nuclei–Multiple pathways, multiple mechanisms?
JD Urrutia Desmaison, RW Sala, A Ayyaz… - Frontiers in Systems …, 2023 - frontiersin.org
Fear learning is mediated by a large network of brain structures and the understanding of
their roles and interactions is constantly progressing. There is a multitude of anatomical and …
their roles and interactions is constantly progressing. There is a multitude of anatomical and …
Selection for reduced fear of humans changes brain and cerebellum size in red junglefowl in line with effects of chicken domestication
A central part of the domestication syndrome is a reduction in relative brain size. In chickens,
it has previously been shown that domesticated birds have smaller relative brain mass, but …
it has previously been shown that domesticated birds have smaller relative brain mass, but …
Intrinsic plasticity of Purkinje cell serves homeostatic regulation of fear memory
Two forms of plasticity, synaptic and intrinsic, are neural substrates for learning and memory.
Abnormalities in homeostatic plasticity cause severe neuropsychiatric diseases, such as …
Abnormalities in homeostatic plasticity cause severe neuropsychiatric diseases, such as …
Cerebellar output neurons impair non-motor behaviors by altering development of extracerebellar connectivity
The capacity of the brain to compensate for insults during development depends on the type
of cell loss, whereas the consequences of genetic mutations in the same neurons are …
of cell loss, whereas the consequences of genetic mutations in the same neurons are …
CK2 negatively regulates the extinction of remote fear memory
J Yang, L Lin, GJ Zou, LF Wang, F Li, CQ Li… - Behavioural Brain …, 2024 - Elsevier
Cognitive behavioral therapy, rooted in exposure therapy, is currently the primary approach
employed in the treatment of anxiety-related conditions, including post-traumatic stress …
employed in the treatment of anxiety-related conditions, including post-traumatic stress …
The cerebellum and its connections to other brain structures involved in motor and non-motor functions: a comprehensive review
The cerebellum has a large network of neurons that communicate with several brain
structures and participate in different functions. Recent studies have demonstrated that the …
structures and participate in different functions. Recent studies have demonstrated that the …