Towards a deeper understanding of the vaginal microbiota

M France, M Alizadeh, S Brown, B Ma, J Ravel - Nature microbiology, 2022 - nature.com
The human vaginal microbiota is a critical determinant of vaginal health. These communities
live in close association with the vaginal epithelium and rely on host tissues for resources …

Contribution of Lactobacillus iners to Vaginal Health and Diseases: A Systematic Review

N Zheng, R Guo, J Wang, W Zhou… - Frontiers in cellular and …, 2021 - frontiersin.org
Lactobacillus iners, first described in 1999, is a prevalent bacterial species of the vaginal
microbiome. As L. iners does not easily grow on de Man-Rogosa-Sharpe agar, but can grow …

Microbiome datasets are compositional: and this is not optional

GB Gloor, JM Macklaim, V Pawlowsky-Glahn… - Frontiers in …, 2017 - frontiersin.org
Datasets collected by high-throughput sequencing (HTS) of 16S rRNA gene amplimers,
metagenomes or metatranscriptomes are commonplace and being used to study human …

The Vaginal Microenvironment: The Physiologic Role of Lactobacilli

E Amabebe, DOC Anumba - Frontiers in medicine, 2018 - frontiersin.org
In addition to being a passage for sperm, menstruum, and the baby, the human vagina and
its microbiota can influence conception, pregnancy, the mode and timing of delivery, and the …

[HTML][HTML] The Immune Escape Mechanisms of Mycobacterium Tuberculosis

W Zhai, F Wu, Y Zhang, Y Fu, Z Liu - International journal of molecular …, 2019 - mdpi.com
Epidemiological data from the Center of Disease Control (CDC) and the World Health
Organization (WHO) statistics in 2017 show that 10.0 million people around the world …

[HTML][HTML] The role of lactic acid production by probiotic Lactobacillus species in vaginal health

G Tachedjian, M Aldunate, CS Bradshaw… - Research in …, 2017 - Elsevier
Vaginal eubiosis is characterised by beneficial lactobacillus-dominated microbiota. In
contrast, vaginal dysbiosis (eg bacterial vaginosis, BV), characterised by an overgrowth of …

Understanding human health through metatranscriptomics

T Ojala, E Kankuri, M Kankainen - Trends in Molecular Medicine, 2023 - cell.com
Metatranscriptomics has revolutionized our ability to explore and understand transcriptional
programs in microbial communities. Moreover, it has enabled us to gain deeper and more …

Roles of the microbiota of the female reproductive tract in gynecological and reproductive health

B Zhu, Z Tao, L Edupuganti, MG Serrano… - … and Molecular Biology …, 2022 - journals.asm.org
The microbiome of the female reproductive tract defies the convention that high biodiversity
is a hallmark of an optimal ecosystem. Although not universally true, a homogeneous …

Lactobacillus iners: friend or foe?

MI Petrova, G Reid, M Vaneechoutte, S Lebeer - Trends in microbiology, 2017 - cell.com
The vaginal microbial community is typically characterized by abundant lactobacilli.
Lactobacillus iners, a fairly recently detected species, is frequently present in the vaginal …

The vaginal microbiota, host defence and reproductive physiology

SB Smith, J Ravel - The Journal of physiology, 2017 - Wiley Online Library
The interaction between the human host and the vaginal microbiota is highly dynamic. Major
changes in the vaginal physiology and microbiota over a woman's lifetime are largely …