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Mathematical models of tumor cell proliferation: A review of the literature
Introduction: A defining hallmark of cancer is aberrant cell proliferation. Efforts to understand
the generative properties of cancer cells span all biological scales: from genetic deviations …
the generative properties of cancer cells span all biological scales: from genetic deviations …
[HTML][HTML] Crosstalk between HER2 and PD-1/PD-L1 in breast cancer: from clinical applications to mathematical models
Breast cancer is one of the major causes of mortality in women worldwide. The most
aggressive breast cancer subtypes are human epidermal growth factor receptor-positive …
aggressive breast cancer subtypes are human epidermal growth factor receptor-positive …
Quantification of long-term doxorubicin response dynamics in breast cancer cell lines to direct treatment schedules
While acquired chemoresistance is recognized as a key challenge to treating many types of
cancer, the dynamics with which drug sensitivity changes after exposure are poorly …
cancer, the dynamics with which drug sensitivity changes after exposure are poorly …
A mathematical model of breast tumor progression based on immune infiltration
Breast cancer is the most prominent type of cancer among women. Understanding the
microenvironment of breast cancer and the interactions between cells and cytokines will …
microenvironment of breast cancer and the interactions between cells and cytokines will …
Using mathematical modelling and AI to improve delivery and efficacy of therapies in cancer
Mathematical modelling has proven to be a valuable tool in predicting the delivery and
efficacy of molecular, antibody-based, nano and cellular therapy in solid tumours …
efficacy of molecular, antibody-based, nano and cellular therapy in solid tumours …
Mathematical modeling of tumor growth and treatment: Triple negative breast cancer
HC Wei - Mathematics and Computers in Simulation, 2023 - Elsevier
In this study, a mathematical model of triple negative breast cancer (TNBC) with checkpoint
inhibitor immunotherapy is proposed. The mathematical model includes interactions …
inhibitor immunotherapy is proposed. The mathematical model includes interactions …
Analysis and modeling of cancer drug responses using cell cycle phase-specific rate effects
Identifying effective therapeutic treatment strategies is a major challenge to improving
outcomes for patients with breast cancer. To gain a comprehensive understanding of how …
outcomes for patients with breast cancer. To gain a comprehensive understanding of how …
Experimentally-driven mathematical modeling to improve combination targeted and cytotoxic therapy for HER2+ breast cancer
The goal of this study is to experimentally and computationally investigate combination
trastuzumab-paclitaxel therapies and identify potential synergistic effects due to sequencing …
trastuzumab-paclitaxel therapies and identify potential synergistic effects due to sequencing …
Mathematical modelling of trastuzumab-induced immune response in an in vivo murine model of HER2+ breast cancer
The goal of this study is to develop an integrated, mathematical–experimental approach for
understanding the interactions between the immune system and the effects of trastuzumab …
understanding the interactions between the immune system and the effects of trastuzumab …
Translational models of tumor angiogenesis: a nexus of in silico and in vitro models
Emerging evidence shows that endothelial cells are not only the building blocks of vascular
networks that enable oxygen and nutrient delivery throughout a tissue but also serve as a …
networks that enable oxygen and nutrient delivery throughout a tissue but also serve as a …