Contrast‐enhanced MicroCT for virtual 3D anatomical pathology of biological tissues: a literature review

S de Bournonville, S Vangrunderbeeck… - Contrast media & …, 2019 - Wiley Online Library
To date, the combination of histological sectioning, staining, and microscopic assessment of
the 2D sections is still the golden standard for structural and compositional analysis of …

Tissue engineered drug delivery vehicles: Methods to monitor and regulate the release behavior

CJ Gil, L Li, B Hwang, M Cadena, AS Theus… - Journal of Controlled …, 2022 - Elsevier
Tissue engineering is a rapidly evolving, multidisciplinary field that aims at generating or
regenerating 3D functional tissues for in vitro disease modeling and drug screening …

Accelerating functional gene discovery in osteoarthritis

NC Butterfield, KF Curry, J Steinberg… - Nature …, 2021 - nature.com
Osteoarthritis causes debilitating pain and disability, resulting in a considerable
socioeconomic burden, yet no drugs are available that prevent disease onset or …

Using mouse models to investigate the pathophysiology, treatment, and prevention of post‐traumatic osteoarthritis

CL Blaker, EC Clarke, CB Little - Journal of Orthopaedic …, 2017 - Wiley Online Library
Post‐traumatic osteoarthritis (PTOA) is defined by its development after joint injury. Factors
contributing to the risk of PTOA occurring, the rate of progression, and degree of associated …

In vivo tracking of tissue engineered constructs

CJ Gil, ML Tomov, AS Theus, A Cetnar, M Mahmoudi… - Micromachines, 2019 - mdpi.com
To date, the fields of biomaterials science and tissue engineering have shown great promise
in creating bioartificial tissues and organs for use in a variety of regenerative medicine …

Challenges and opportunities for small volumes delivery into the skin

M Mercuri, D Fernandez Rivas - Biomicrofluidics, 2021 - pubs.aip.org
Each individual's skin has its own features, such as strength, elasticity, or permeability to
drugs, which limits the effectiveness of one-size-fits-all approaches typically found in …

Nanotechnology and osteoarthritis. Part 1: clinical landscape and opportunities for advanced diagnostics

TB Lawson, JTA Mäkelä, T Klein… - Journal of …, 2021 - Wiley Online Library
Osteoarthritis (OA) is a disease of the entire joint, often triggered by cartilage injury,
mediated by a cascade of inflammatory pathways involving a complex interplay among …

Cationic poly-l-lysine-encapsulated melanin nanoparticles as efficient photoacoustic agents targeting to glycosaminoglycans for the early diagnosis of articular …

L Chen, Y Ji, X Hu, C Cui, H Liu, Y Tang, B Qi, Y Niu… - Nanoscale, 2018 - pubs.rsc.org
Cartilage degeneration is the hallmark of osteoarthritis (OA) and its early diagnosis is
essential for effective cartilage repair. However, until now, there was still a lack of imaging …

The emerging landscape of nanotheranostic-based diagnosis and therapy for osteoarthritis

S **ao, L Chen - Journal of Controlled Release, 2020 - Elsevier
Osteoarthritis (OA) is a common degenerative disease involving numerous joint tissues and
cells, with a growing rate in prevalence that ultimately results in a negative social impact …

Recent advances in articular cartilage evaluation using computed tomography and magnetic resonance imaging

BB Nelson, CE Kawcak, MF Barrett… - Equine veterinary …, 2018 - Wiley Online Library
Articular cartilage is a critical joint tissue and its evaluation remains a diagnostic challenge
in horses. Coupled with a poor capacity for healing, early degenerative changes in articular …