Designing synthetic microbial communities with the capacity to upcycle fermentation byproducts to increase production yields

R Rafieenia, C Klemm, P Hapeta, J Fu, MG García… - Trends in …, 2024 - cell.com
Microbial cell factories, which convert feedstocks into a product of value, have the potential
to help transition toward a bio-based economy with more sustainable ways to produce food …

Cyanobacteria as cell factories for the photosynthetic production of sucrose

M Santos-Merino, L Yun, DC Ducat - Frontiers in Microbiology, 2023 - frontiersin.org
Biofuels and other biologically manufactured sustainable goods are growing in popularity
and demand. Carbohydrate feedstocks required for industrial fermentation processes have …

[HTML][HTML] Synthetic, marine, light-driven, autotroph-heterotroph co-culture system for sustainable β-caryophyllene production

W Chen, YK Park, L Studená, D Bell, P Hapeta… - Bioresource …, 2024 - Elsevier
Applying low-cost substrate is critical for sustainable bioproduction. Co-culture of
phototrophic and heterotrophic microorganisms can be a promising solution as they can use …

Synthetic Biology of Natural Products Engineering: Recent Advances Across the Discover–Design–Build–Test–Learn Cycle

J Foldi, JA Connolly, E Takano… - ACS Synthetic Biology, 2024 - ACS Publications
Advances in genome engineering and associated technologies have reinvigorated natural
products research. Here we highlight the latest developments in the field across the discover …

Light management by algal aggregates in living photosynthetic hydrogels

ST Chua, A Smith, S Murthy… - Proceedings of the …, 2024 - National Acad Sciences
Rapid progress in algal biotechnology has triggered a growing interest in hydrogel-
encapsulated microalgal cultivation, especially for the engineering of functional …

Rational construction of synthetic consortia: Key considerations and model-based methods for guiding the development of a novel biosynthesis platform

Y Liu, B Xue, H Liu, S Wang, H Su - Biotechnology Advances, 2024 - Elsevier
The rapid development of synthetic biology has significantly improved the capabilities of
mono-culture systems in converting different substrates into various value-added bio …

[HTML][HTML] Engineering highly productive cyanobacteria towards carbon negative emissions technologies

AJ Victoria, MJ Astbury, AJ McCormick - Current opinion in biotechnology, 2024 - Elsevier
Highlights•Highly productive cyanobacteria could play a key role in carbon sequestration.•
Synthetic biology tools can unlock the potential of new strains for bioproduction.•Coculture …

Addressing genome scale design tradeoffs in Pseudomonas putida for bioconversion of an aromatic carbon source

D Banerjee, J Menasalvas, Y Chen, JW Gin… - npj Systems Biology …, 2025 - nature.com
Genome-scale metabolic models (GSMM) are commonly used to identify gene deletion sets
that result in growth coupling and pairing product formation with substrate utilization and can …

Synthetic Light‐Driven Consortia for Carbon‐Negative Biosynthesis

C Li, H Zheng, H Li, L Liu, J Wang, J Ni - ChemBioChem, 2023 - Wiley Online Library
Synthetic light‐driven consortia composed of phototrophs and heterotrophs have attracted
increasing attention owing to their potential to be used in sustainable biotechnology. In …

Strategies and tools to construct stable and efficient artificial coculture systems as biosynthetic platforms for biomass conversion

X Song, Y Ju, L Chen, W Zhang - Biotechnology for Biofuels and …, 2024 - Springer
Inspired by the natural symbiotic relationships between diverse microbial members,
researchers recently focused on modifying microbial chassis to create artificial coculture …