ApoE is the major lipid and cholesterol carrier in the CNS. There are three major human
polymorphisms, apoE2, apoE3, and apoE4, and the genetic expression of APOE4 is one of …

The enteric nervous system (ENS) is the largest division of the peripheral nervous system
and closely resembles components and functions of the central nervous system. Although …

Galectin-3 (Gal-3) regulates basic cellular functions such as cell–cell and cell–matrix
interactions, growth, proliferation, differentiation, and inflammation. It is not surprising …

There is increasing evidence of the influence of the gut microbiota on hypertension and its
complications, such as chronic kidney disease, stroke, heart failure, and myocardial …

After cerebral ischemia, events like neural plasticity and tissue reorganization intervene in
lesioned and non-lesioned areas of the brain. These processes are tightly related to …

Central nervous system injuries may lead to the disorders of the hypothalamic‐pituitary‐
adrenal axis, autonomic nervous system, and enteric nervous system. These effects then …

Microbiota research, in particular that of the gut, has recently gained much attention in
medical research owing to technological advances in metagenomics and metabolomics …

Galectin-3 (Gal-3) is the only chimeric protein in the galectin family. Gal-3 structure
comprises unusual tandem repeats of proline and glycine-rich short stretches bound to a …

There is a plethora of evidence to suggest that Galectin-3 plays an important role in normal
functions of mammalian cells, as well as in different pathogenic conditions. This review …

Among all the biological entities involved in the immune response, galectins, a family of
glycan-binding proteins, have been described as key in immune cell homeostasis and …