Perspective: evolutionary developmental biology and the problem of variation

DL Stern - Evolution, 2000 - Wiley Online Library
One of the oldest problems in evolutionary biology remains largely unsolved. Which
mutations generate evolutionarily relevant phenotypic variation? What kinds of molecular …

The role of WOX genes in flower development

E Costanzo, C Trehin, M Vandenbussche - Annals of botany, 2014 - academic.oup.com
Background WOX (Wuschel-like homeobOX) genes form a family of plant-specific
HOMEODOMAIN transcription factors, the members of which play important developmental …

[HTML][HTML] Polycomb-dependent regulatory contacts between distant Hox loci in Drosophila

F Bantignies, V Roure, I Comet, B Leblanc… - Cell, 2011 - cell.com
Summary In Drosophila melanogaster, Hox genes are organized in an anterior and a
posterior cluster, called Antennapedia complex and bithorax complex, located on the same …

A role of Ultrabithorax in morphological differences between Drosophila species

DL Stern - Nature, 1998 - nature.com
The mechanisms underlying the evolution of morphology are poorly understood,. Distantly
related taxa sometimes exhibit correlations between morphological differences and patterns …

[PDF][PDF] Hox genes, homeosis and the evolution of segment identity: no need for hopeless monsters

M Akam - International Journal of Developmental …, 1998 - cienciaescolar.wordpress.com
Significant changes have occurred in the developmental role of Hox genes, even within
groups of arthropods that already have complex body plans and many different segment …

Overexpression of the homeobox gene HOXC8 in human prostate cancer correlates with loss of tumor differentiation*

D Waltregny, Y Alami, N Clausse, J Leval… - The …, 2002 - Wiley Online Library
BACKGROUND Homeobox (HOX)-containing proteins have been identified as regulators
controlling the coordinated expression of genes involved in development and differentiation …

HOXA9 is underexpressed in cervical cancer cells and its restoration decreases proliferation, migration and expression of epithelial-to-mesenchymal transition genes

L Alvarado-Ruiz, MG Martinez-Silva… - Asian Pacific Journal …, 2016 - journal.waocp.org
HOX transcription factors are evolutionarily conserved in many different species and are
involved in important cellular processes such as morphogenesis, differentiation, and …

Segment-specific prevention of pioneer neuron apoptosis by cell-autonomous, postmitotic Hox gene activity

I Miguel-Aliaga, S Thor - 2004 - journals.biologists.com
In vertebrates, neurons often undergo apoptosis after differentiating and extending their
axons. By contrast, in the develo** nervous system of invertebrate embryos apoptosis …

Trilobite tagmosis and body patterning from morphological and developmental perspectives

NC Hughes - Integrative and Comparative Biology, 2003 - academic.oup.com
The Trilobita were characterized by a cephalic region in which the biomineralized
exoskeleton showed relatively high morphological differentiation among a taxonomically …

[HTML][HTML] Common origin of insect trachea and endocrine organs from a segmentally repeated precursor

C Sánchez-Higueras, S Sotillos, JCG Hombría - Current Biology, 2014 - cell.com
Segmented organisms have serially repeated structures [1] that become specialized in some
segments [2]. We show here that the Drosophila corpora allata, prothoracic glands, and …