Mitochondria carry their own genetic information encoding for a subset of protein-coding
genes and translational machinery essential for cellular respiration and metabolism. Despite …

Mitochondria are believed to have originated through an ancient endosymbiotic process in
which proteobacteria were captured and co-opted for energy production and cellular …

Mammalian genes were long thought to be constrained within somatic cells in most cell
types. This concept was challenged recently when cellular organelles including …

Mitochondria transfer is a recently described phenomenon in which donor cells deliver
mitochondria to acceptor cells,–. One possible consequence of mitochondria transfer is …

Intercellular signaling and component conduction are essential for multicellular organisms'
homeostasis, and mitochondrial transcellular transport is a key example of such cellular …

Background Mitochondria play a critical role in the production of cell energy and the
regulation of cell death. Therefore, mitochondria orchestrate numerous cell effector …

Mitochondria's role as engines and beacons of metabolism and determinants of cellular
health is being redefined through their therapeutic application as “Living Drugs”(LDs) …

Reprogramming tumor‐associated macrophages (TAMs) to an inflammatory phenotype
effectively increases the potential of immune checkpoint blockade (ICB) therapy. Artificial …

Mitochondrial diseases (MDs) are inherited genetic conditions characterized by pathogenic
mutations in nuclear DNA (nDNA) or mitochondrial DNA (mtDNA). Current therapies are still …

To date, Alzheimer's disease (AD) has grown to be a predominant health challenge that
disturbs the elderly population. Studies have shown that mitochondrial dysfunction is one of …