The surprising discovery that the diatomic gas nitric oxide (NO) is generated by mammalian
cells and serves to regulate a multitude of physiological processes has continued to …

Background and Purpose—The purpose of these guidelines is to provide an up-to-date
comprehensive set of recommendations in a single document for clinicians caring for adult …

Small vessel disease is a disorder of cerebral microvessels that causes white matter
hyperintensities and several other common abnormalities (eg, recent small subcortical …

The optimal management of post-stroke cognitive impairment remains controversial. These
joint European Stroke Organisation (ESO) and European Academy of Neurology (EAN) …

The optimal blood pressure (BP) management in acute ischaemic stroke (AIS) and acute
intracerebral haemorrhage (ICH) remains controversial. These European Stroke …

2018 Guidelines for the Early Management of Patients With Acute Ischemic Stroke: A
Guideline for Healthcare Professionals From the American Heart Association/American Stroke …

Aims The expression of GADD153 (growth arrest and DNA damage-inducible gene 153), an
apoptosis-regulated gene, increases during endoplasmic reticulum (ER) stress. How …

Importance DL-3-n-butylphthalide (NBP) is a drug for treating acute ischemic stroke and may
play a neuroprotective role by acting on multiple active targets. The efficacy of NBP in …

Post-stroke dementia (PSD) or post-stroke cognitive impairment (PSCI) may affect up to one
third of stroke survivors. Various definitions of PSCI and PSD have been described. We …

Background Tranexamic acid can prevent death due to bleeding after trauma and post-
partum haemorrhage. We aimed to assess whether tranexamic acid reduces haematoma …