Emerging neuroprotective strategies for the treatment of ischemic stroke: An overview of clinical and preclinical studies
S Paul, E Candelario-Jalil - Experimental neurology, 2021 - Elsevier
Stroke is the leading cause of disability and thesecond leading cause of death worldwide.
With the global population aged 65 and over growing faster than all other age groups, the …
With the global population aged 65 and over growing faster than all other age groups, the …
Neuroinflammation in neurodegenerative disorders: the roles of microglia and astrocytes
HS Kwon, SH Koh - Translational neurodegeneration, 2020 - Springer
Neuroinflammation is associated with neurodegenerative diseases, such as Alzheimer's
disease, Parkinson's disease, and amyotrophic lateral sclerosis. Microglia and astrocytes …
disease, Parkinson's disease, and amyotrophic lateral sclerosis. Microglia and astrocytes …
Neuroinflammation: friend and foe for ischemic stroke
Stroke, the third leading cause of death and disability worldwide, is undergoing a change in
perspective with the emergence of new ideas on neurodegeneration. The concept that …
perspective with the emergence of new ideas on neurodegeneration. The concept that …
Glial cells: role of the immune response in ischemic stroke
S Xu, J Lu, A Shao, JH Zhang, J Zhang - Frontiers in immunology, 2020 - frontiersin.org
Ischemic stroke, which accounts for 75–80% of all strokes, is the predominant cause of
morbidity and mortality worldwide. The post-stroke immune response has recently emerged …
morbidity and mortality worldwide. The post-stroke immune response has recently emerged …
Protective functions of reactive astrocytes following central nervous system insult
M Linnerbauer, V Rothhammer - Frontiers in immunology, 2020 - frontiersin.org
Astrocytes play important roles in numerous central nervous system disorders including
autoimmune inflammatory, hypoxic, and degenerative diseases such as Multiple Sclerosis …
autoimmune inflammatory, hypoxic, and degenerative diseases such as Multiple Sclerosis …
Astrocytes: key regulators of neuroinflammation
E Colombo, C Farina - Trends in immunology, 2016 - cell.com
Astrocytes are crucial regulators of innate and adaptive immune responses in the injured
central nervous system. Depending on timing and context, astrocyte activity may exacerbate …
central nervous system. Depending on timing and context, astrocyte activity may exacerbate …
Astrocyte-immune cell interactions in physiology and pathology
Astrocytes play both physiological and pathological roles in maintaining central nervous
system (CNS) function. Here, we review the varied functions of astrocytes and how these …
system (CNS) function. Here, we review the varied functions of astrocytes and how these …
The influence of neuroinflammation in Autism Spectrum Disorder
Abstract Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterised
by deficits in social communication and restricted or repetitive behaviours. The clinical …
by deficits in social communication and restricted or repetitive behaviours. The clinical …
Astrocyte barriers to neurotoxic inflammation
MV Sofroniew - Nature Reviews Neuroscience, 2015 - nature.com
Astrocytes form borders (glia limitans) that separate neural from non-neural tissue along
perivascular spaces, meninges and tissue lesions in the CNS. Transgenic loss-of-function …
perivascular spaces, meninges and tissue lesions in the CNS. Transgenic loss-of-function …
Crosstalk between the oxidative stress and glia cells after stroke: from mechanism to therapies
Stroke is the second leading cause of global death and is characterized by high rates of
mortality and disability. Oxidative stress is accompanied by other pathological processes …
mortality and disability. Oxidative stress is accompanied by other pathological processes …