Organoid and spheroid tumor models: techniques and applications
S Gunti, ATK Hoke, KP Vu, NR London Jr - Cancers, 2021 - mdpi.com
Simple Summary Cell cultures can be carried out in three dimensions (3D). Organoids and
spheroids are different 3D cell culture models that can be cultured with different techniques …
spheroids are different 3D cell culture models that can be cultured with different techniques …
New frontiers in colorectal cancer treatment combining nanotechnology with photo-and radiotherapy
Simple Summary Although colorectal cancer is the third most common type of cancer, its
treatment strategies still have room for improvement, as current techniques carry risks that …
treatment strategies still have room for improvement, as current techniques carry risks that …
[HTML][HTML] Organoid intelligence: Integration of organoid technology and artificial intelligence in the new era of in vitro models
H Shi, A Kowalczewski, D Vu, X Liu, A Salekin… - Medicine in novel …, 2024 - Elsevier
Organoid Intelligence ushers in a new era by seamlessly integrating cutting-edge organoid
technology with the power of artificial intelligence. Organoids, three-dimensional miniature …
technology with the power of artificial intelligence. Organoids, three-dimensional miniature …
Implications of intratumor heterogeneity on consensus molecular subtype (CMS) in colorectal cancer
Simple Summary Colorectal cancer (CRC) has been divided into four consensus molecular
subtypes (CMS) using the unsupervised clustering of bulk transcriptomic data. The CMS …
subtypes (CMS) using the unsupervised clustering of bulk transcriptomic data. The CMS …
Application progress of organoids in colorectal cancer
L Luo, Y Ma, Y Zheng, J Su, G Huang - Frontiers in Cell and …, 2022 - frontiersin.org
Currently, colorectal cancer is still the third leading cause of cancer-related mortality, and the
incidence is rising. It is a long time since the researchers used cancer cell lines and animals …
incidence is rising. It is a long time since the researchers used cancer cell lines and animals …
Single cell transcriptome in colorectal cancer—current updates on its application in metastasis, chemoresistance and the roles of circulating tumor cells
Colorectal cancer (CRC) is among the most common cancer worldwide, a challenge for
research, and a model for studying the molecular mechanisms involved in its development …
research, and a model for studying the molecular mechanisms involved in its development …
The potential application of organoids in breast cancer research and treatment
N Ebrahimi, A Nasr Esfahani, S Samizade, A Mansouri… - Human genetics, 2022 - Springer
Tumor heterogeneity is a major challenge for breast cancer researchers who have struggled
to find effective treatments despite recent advances in oncology. Although the use of 2D cell …
to find effective treatments despite recent advances in oncology. Although the use of 2D cell …
Reconstructing the tumor architecture into organoids
Cancer remains a leading health burden worldwide. One of the challenges hindering cancer
therapy development is the substantial discrepancies between the existing cancer models …
therapy development is the substantial discrepancies between the existing cancer models …
Capturing tumour heterogeneity in pre-and post-chemotherapy colorectal cancer ascites-derived cells using single-cell RNA-sequencing
Malignant ascites is an abnormal accumulation of fluid within the peritoneal cavity, caused
by metastasis of several types of cancers, including colorectal cancer (CRC). Cancer cells in …
by metastasis of several types of cancers, including colorectal cancer (CRC). Cancer cells in …
[HTML][HTML] The progress and clinical application of breast cancer organoids
J Yu, W Huang - International Journal of Stem Cells, 2020 - synapse.koreamed.org
Breast cancer is the malignant tumor with the highest incidence in women. Nowadays, the
objects in vitro of models of this disease are mainly from breast cancer cell lines and patient …
objects in vitro of models of this disease are mainly from breast cancer cell lines and patient …