Hidradenitis suppurativa: an update on epidemiology, phenotypes, diagnosis, pathogenesis, comorbidities and quality of life

TV Nguyen, G Damiani, LAV Orenstein… - Journal of the …, 2021‏ - Wiley Online Library
Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease that severely impairs
patients' quality of life. It is characterized by recurrent painful nodules, abscesses and …

Hidradenitis suppurativa: epidemiology, clinical presentation, and pathogenesis

SR Goldburg, BE Strober, MJ Payette - Journal of the American Academy …, 2020‏ - Elsevier
Hidradenitis suppurativa (HS) is an inflammatory disorder that is characterized by chronic
deep-seated nodules, abscesses, fistulae, sinus tracts, and scars in the axilla, inguinal area …

Secukinumab in moderate-to-severe hidradenitis suppurativa (SUNSHINE and SUNRISE): week 16 and week 52 results of two identical, multicentre, randomised …

AB Kimball, GBE Jemec, A Alavi, Z Reguiai, AB Gottlieb… - The Lancet, 2023‏ - thelancet.com
Background Few therapeutic options are available for patients with moderate-to-severe
hidradenitis suppurativa. We aimed to assess the efficacy of secukinumab in patients with …

Two phase 3 trials of adalimumab for hidradenitis suppurativa

AB Kimball, MM Okun, DA Williams… - … England Journal of …, 2016‏ - Mass Medical Soc
Background Hidradenitis suppurativa is a painful, chronic inflammatory skin disease with
few options for effective treatment. In a phase 2 trial, adalimumab, an antibody against tumor …

Development and validation of the International Hidradenitis Suppurativa Severity Score System (IHS4), a novel dynamic scoring system to assess HS severity

CC Zouboulis, T Tzellos, A Kyrgidis… - British Journal of …, 2017‏ - academic.oup.com
Background A validated tool for the dynamic severity assessment of hidradenitis
suppurativa/acne inversa (HS) is lacking. Objectives To develop and validate a novel …

Hidradenitis suppurativa/acne inversa: a practical framework for treatment optimization–systematic review and recommendations from the HS ALLIANCE working …

CC Zouboulis, FG Bechara… - Journal of the …, 2019‏ - Wiley Online Library
Hidradenitis suppurativa (HS)/acne inversa is a debilitating chronic disease that remains
poorly understood and difficult to manage. Clinical practice is variable, and there is a need …

Hidradenitis suppurativa/acne inversa: criteria for diagnosis, severity assessment, classification and disease evaluation

CC Zouboulis, V Del Marmol, U Mrowietz, EP Prens… - Dermatology, 2015‏ - karger.com
Background: Hidradenitis suppurativa/acne inversa (HS) is a chronic, inflammatory,
recurrent, debilitating disease, which inflicts a significant burden on patients and is …

[HTML][HTML] Current medical and surgical treatment of hidradenitis suppurativa—a comprehensive review

L Ocker, N Abu Rached, C Seifert, C Scheel… - Journal of Clinical …, 2022‏ - mdpi.com
Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease presenting with
recurrent inflammatory lesions in intertriginous body regions. HS has a pronounced impact …

Safety and efficacy of anakinra in severe hidradenitis suppurativa: a randomized clinical trial

V Tzanetakou, T Kanni, S Giatrakou, A Katoulis… - JAMA …, 2016‏ - jamanetwork.com
Importance Hidradenitis suppurativa (HS) is a common skin disorder in which excessive
inflammation is believed to have an important role. There is no specific therapy for HS …

Evidence-based approach to the treatment of hidradenitis suppurativa/acne inversa, based on the European guidelines for hidradenitis suppurativa

W Gulliver, CC Zouboulis, E Prens, GBE Jemec… - Reviews in Endocrine …, 2016‏ - Springer
Hidradenitis suppurativa/acne inversa (HS) is a chronic inflammatory skin disease
characterized by painful, recurrent nodules and abscesses that rupture and lead to sinus …