Prostate Cancer Biomarkers: From diagnosis to prognosis and precision-guided therapeutics
M Adamaki, V Zoumpourlis - Pharmacology & therapeutics, 2021 - Elsevier
Prostate cancer (PCa) is one of the most commonly diagnosed malignancies and among the
leading causes of cancer-related death worldwide. It is a highly heterogeneous disease …
leading causes of cancer-related death worldwide. It is a highly heterogeneous disease …
An autophagy assay reveals the ESCRT-III component CHMP2A as a regulator of phagophore closure
The mechanism of phagophore closure remains unclear due to technical limitations in
distinguishing unclosed and closed autophagosomal membranes. Here, we report the …
distinguishing unclosed and closed autophagosomal membranes. Here, we report the …
Membrane re-modelling by BAR domain superfamily proteins via molecular and non-molecular factors
T Nishimura, N Morone… - Biochemical Society …, 2018 - portlandpress.com
Lipid membranes are structural components of cell surfaces and intracellular organelles.
Alterations in lipid membrane shape are accompanied by numerous cellular functions …
Alterations in lipid membrane shape are accompanied by numerous cellular functions …
VPS37A directs ESCRT recruitment for phagophore closure
The process of phagophore closure requires the endosomal sorting complex required for
transport III (ESCRT-III) subunit CHMP2A and the AAA ATPase VPS4, but their regulatory …
transport III (ESCRT-III) subunit CHMP2A and the AAA ATPase VPS4, but their regulatory …
Bile acids and ceramide overcome the entry restriction for GII. 3 human norovirus replication in human intestinal enteroids
K Murakami, VR Tenge… - Proceedings of the …, 2020 - National Acad Sciences
Human noroviruses (HuNoVs) cause sporadic and epidemic outbreaks of gastroenteritis in
all age groups worldwide. We previously reported that stem cell-derived human intestinal …
all age groups worldwide. We previously reported that stem cell-derived human intestinal …
Palmitoylation targets the calcineurin phosphatase to the phosphatidylinositol 4-kinase complex at the plasma membrane
Calcineurin, the conserved protein phosphatase and target of immunosuppressants, is a
critical mediator of Ca2+ signaling. Here, to discover calcineurin-regulated processes we …
critical mediator of Ca2+ signaling. Here, to discover calcineurin-regulated processes we …
An N-terminal conserved region in human Atg3 couples membrane curvature sensitivity to conjugase activity during autophagy
During autophagy the enzyme Atg3 catalyzes the covalent conjugation of LC3 to the amino
group of phosphatidylethanolamine (PE) lipids, which is one of the key steps in …
group of phosphatidylethanolamine (PE) lipids, which is one of the key steps in …
Alveolar-capillary endocytosis and trafficking in acute lung injury and acute respiratory distress syndrome
V Kryvenko, I Vadász - Frontiers in Immunology, 2024 - frontiersin.org
Acute respiratory distress syndrome (ARDS) is associated with high morbidity and mortality
but lacks specific therapeutic options. Diverse endocytic processes play a key role in all …
but lacks specific therapeutic options. Diverse endocytic processes play a key role in all …
Quality changes in gazami crab (Portunus trituberculatus) during refrigeration
Y Ren, J Sun, X Mao - Food Chemistry, 2024 - Elsevier
Gazami crab (Portunus trituberculatus) is prone to spoilage during storage and
transportation. More research is needed to determine how to reliably show its freshness and …
transportation. More research is needed to determine how to reliably show its freshness and …
[HTML][HTML] Endophilin-B regulates autophagy during synapse development and neurodegeneration
S Hernandez-Diaz, S Ghimire… - Neurobiology of …, 2022 - Elsevier
Synapses are critical for neuronal communication and brain function. To maintain neuronal
homeostasis, synapses rely on autophagy. Autophagic alterations cause neurodegeneration …
homeostasis, synapses rely on autophagy. Autophagic alterations cause neurodegeneration …