Coronavirus envelope protein: current knowledge
Abstract Background Coronaviruses (CoVs) primarily cause enzootic infections in birds and
mammals but, in the last few decades, have shown to be capable of infecting humans as …
mammals but, in the last few decades, have shown to be capable of infecting humans as …
Human coronavirus: host-pathogen interaction
TS Fung, DX Liu - Annual review of microbiology, 2019 - annualreviews.org
Human coronavirus (HCoV) infection causes respiratory diseases with mild to severe
outcomes. In the last 15 years, we have witnessed the emergence of two zoonotic, highly …
outcomes. In the last 15 years, we have witnessed the emergence of two zoonotic, highly …
SKP2 attenuates autophagy through Beclin1-ubiquitination and its inhibition reduces MERS-Coronavirus infection
Autophagy is an essential cellular process affecting virus infections and other diseases and
Beclin1 (BECN1) is one of its key regulators. Here, we identified S-phase kinase-associated …
Beclin1 (BECN1) is one of its key regulators. Here, we identified S-phase kinase-associated …
Autophagy: The spotlight for cellular stress responses
Autophagy is an essential cellular mechanism which plays “housekee**” role in normal
physiological processes including removing of long lived, aggregated and misfolded …
physiological processes including removing of long lived, aggregated and misfolded …
Contribution of autophagy machinery factors to HCV and SARS-CoV-2 replication organelle formation
Positive-strand RNA viruses replicate in close association with rearranged intracellular
membranes. For hepatitis C virus (HCV) and severe acute respiratory syndrome coronavirus …
membranes. For hepatitis C virus (HCV) and severe acute respiratory syndrome coronavirus …
[HTML][HTML] Mammalian hybrid pre-autophagosomal structure HyPAS generates autophagosomes
The biogenesis of mammalian autophagosomes remains to be fully defined. Here, we used
cellular and in vitro membrane fusion analyses to show that autophagosomes are formed …
cellular and in vitro membrane fusion analyses to show that autophagosomes are formed …
Inhibitors of VPS34 and fatty-acid metabolism suppress SARS-CoV-2 replication
Coronaviruses rely on host membranes for entry, establishment of replication centers, and
egress. Compounds targeting cellular membrane biology and lipid biosynthetic pathways …
egress. Compounds targeting cellular membrane biology and lipid biosynthetic pathways …
Taming the Autophagy as a Strategy for Treating COVID-19
Currently, an efficient treatment for COVID-19 is still unavailable, and people are continuing
to die from complications associated with SARS-CoV-2 infection. Thus, the development of …
to die from complications associated with SARS-CoV-2 infection. Thus, the development of …
SARS-CoV-2 and other coronaviruses negatively influence mitochondrial quality control: beneficial effects of melatonin
Coronaviruses (CoVs) are a group of single stranded RNA viruses, of which some of them
such as SARS-CoV, MERS-CoV, and SARS-CoV-2 are associated with deadly worldwide …
such as SARS-CoV, MERS-CoV, and SARS-CoV-2 are associated with deadly worldwide …
Canonical and noncanonical autophagy as potential targets for COVID-19
The SARS-CoV-2 pandemic necessitates a review of the molecular mechanisms underlying
cellular infection by coronaviruses, in order to identify potential therapeutic targets against …
cellular infection by coronaviruses, in order to identify potential therapeutic targets against …