Abstract Lipocalin-2 (LCN-2) is a novel, 198 amino acid adipocytokine also referred to as
neutrophil gelatinase-associated lipocalin (NGAL). LCN-2 is a circulatory protein …

Chronic (neuro) inflammation plays an important role in many age-related central nervous
system (CNS) diseases, including Alzheimer's disease, Parkinson's disease and vascular …

Lipocalin 2 (Lcn2), an innate immune protein, has emerged as a critical iron regulatory
protein during physiological and inflammatory conditions. As a bacteriostatic factor, Lcn2 …

Astrocytes provide structural and functional support for neurons, as well as display
neurotoxic or neuroprotective phenotypes depending upon the presence of an immune or …

Astrocytes are the main support cells of the central nervous system. They also participate in
neuroimmune reactions. In response to pathological and immune stimuli, astrocytes …

Abstract Lipocalin-2 (LCN2) is an acute-phase protein that, by binding to iron-loaded
siderophores, acts as a potent bacteriostatic agent in the iron-depletion strategy of the …

Abstract Lipocalin-2 (LCN2) is an acute phase protein with multiple functions that has
garnered a great deal of interest over the last decade. However, its precise role in the …

Leukocyte migration into the central nervous system (CNS) represents a central process in
the development of neurological diseases with a detrimental inflammatory component …

Abstract Lipocalin-2 (LCN2) is a member of the secreted lipocalin protein family. LCN2 is
also a representative gliocalin that is primarily released by glial cells, as well as acts upon …

Lipocalin 2 (LCN2) is a secreted protein that belongs to the Lipocalins, a group of
transporters of small lipophilic molecules such as steroids, lipopolysaccharides, iron, and …