Asymmetric hydroalkoxylation of alkenes constitutes a redox-neutral and 100% atom-
economical strategy toward enantioenriched oxygenated building blocks from readily …

Chiral phosphoric acids (CPAs) have emerged as powerful organocatalysts for asymmetric
reactions, and applications of computational quantum chemistry have revealed important …

A critical review of the state-of-the-art evidence in support of the mechanisms of
glycosylation reactions is provided. Factors affecting the stability of putative oxocarbenium …

The area of reaction mechanism discovery simulation has taken considerable strides in
recent years. Novel methods that make hypotheses for elementary steps and …

Carbohydrate chemistry is an essential component of the glycosciences and is fundamental
to their progress. This Perspective takes the position that carbohydrate chemistry, or …

Until recently, computational tools were mainly used to explain chemical reactions after
experimental results were obtained. With the rapid development of software and hardware …

The activation of olefins for asymmetric chemical synthesis traditionally relies on transition
metal catalysts. In contrast, biological enzymes with Brønsted acidic sites of appropriate …

The total synthesis and structural elucidation of the antimicrobial sactipeptide enteropeptin A
is reported. Enteropeptin A contains a thioaminoketal group with an unassigned …

Ketohydroperoxides are important in liquid-phase autoxidation and in gas-phase partial
oxidation and pre-ignition chemistry, but because of their low concentration, instability, and …

We reported herein an iridium/silver/acid ternary catalytic system to access
bisbenzannulated [6, 6]‐spiroketals in high efficiency with generally high diastereo‐and …