Tumor abnormality-oriented nanomedicine design

Q Zhou, J **ang, N Qiu, Y Wang, Y Piao, S Shao… - Chemical …, 2023 - ACS Publications
Anticancer nanomedicines have been proven effective in mitigating the side effects of
chemotherapeutic drugs. However, challenges remain in augmenting their therapeutic …

Photodynamic therapy: Innovative approaches for antibacterial and anticancer treatments

M Kolarikova, B Hosikova, H Dilenko… - Medicinal Research …, 2023 - Wiley Online Library
Photodynamic therapy is an alternative treatment mainly for cancer but also for bacterial
infections. This treatment dates back to 1900 when a German medical school graduate …

Nanocarriers address intracellular barriers for efficient drug delivery, overcoming drug resistance, subcellular targeting and controlled release

J Liu, H Cabral, P Mi - Advanced Drug Delivery Reviews, 2024 - Elsevier
The cellular barriers are major bottlenecks for bioactive compounds entering into cells to
accomplish their biological functions, which limits their biomedical applications …

Advanced strategies for overcoming endosomal/lysosomal barrier in nanodrug delivery

C Qiu, F **a, J Zhang, Q Shi, Y Meng, C Wang, H Pang… - Research, 2023 - spj.science.org
Nanocarriers have therapeutic potential to facilitate drug delivery, including biological
agents, small-molecule drugs, and nucleic acids. However, their efficiency is limited by …

Organelle-targeted therapies: a comprehensive review on system design for enabling precision oncology

J Yang, A Griffin, Z Qiang, J Ren - Signal transduction and targeted …, 2022 - nature.com
Cancer is a major threat to human health. Among various treatment methods, precision
therapy has received significant attention since the inception, due to its ability to efficiently …

Concepts of nanoparticle cellular uptake, intracellular trafficking, and kinetics in nanomedicine

ND Donahue, H Acar, S Wilhelm - Advanced drug delivery reviews, 2019 - Elsevier
Nanoparticle-based therapeutics and diagnostics are commonly referred to as
nanomedicine and may significantly impact the future of healthcare. However, the clinical …

Emerging trends in polymerization-induced self-assembly

NJW Penfold, J Yeow, C Boyer, SP Armes - ACS Macro Letters, 2019 - ACS Publications
In this Perspective, we summarize recent progress in polymerization-induced self-assembly
(PISA) for the rational synthesis of block copolymer nanoparticles with various …

Size-tunable strategies for a tumor targeted drug delivery system

W Yu, R Liu, Y Zhou, H Gao - ACS central science, 2020 - ACS Publications
Nanoparticles have been widely used in tumor targeted drug delivery, while the antitumor
effects are not always satisfactory due to the limited penetration and retention. As we all …

Synthesis and applications of anisotropic nanoparticles with precisely defined dimensions

AK Pearce, TR Wilks, MC Arno… - Nature Reviews Chemistry, 2021 - nature.com
Shape and size play powerful roles in determining the properties of a material; controlling
these aspects with precision is therefore an important, fundamental goal of the chemical …

Transmission electron microscopy as a powerful tool to investigate the interaction of nanoparticles with subcellular structures

M Malatesta - International journal of molecular sciences, 2021 - mdpi.com
Nanomedical research necessarily involves the study of the interactions between
nanoparticulates and the biological environment. Transmission electron microscopy has …