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Bioinformatic tools for microRNA dissection
Recently, microRNAs (miRNAs) have emerged as important elements of gene regulatory
networks. MiRNAs are endogenous single-stranded non-coding RNAs (∼ 22-nt long) that …
networks. MiRNAs are endogenous single-stranded non-coding RNAs (∼ 22-nt long) that …
DIANA-miRPath v3. 0: deciphering microRNA function with experimental support
The functional characterization of miRNAs is still an open challenge. Here, we present
DIANA-miRPath v3. 0 (http://www. microrna. gr/miRPathv3) an online software suite …
DIANA-miRPath v3. 0 (http://www. microrna. gr/miRPathv3) an online software suite …
Roles of NF-κB signaling in the regulation of miRNAs impacting on inflammation in cancer
The NF-κB family of transcription factors regulate the expression of genes encoding proteins
and microRNAs (miRNA, miR) precursors that may either positively or negatively regulate a …
and microRNAs (miRNA, miR) precursors that may either positively or negatively regulate a …
Altered microRNA profiles in cerebrospinal fluid exosome in Parkinson disease and Alzheimer disease
YX Gui, H Liu, LS Zhang, W Lv, XY Hu - Oncotarget, 2015 - pmc.ncbi.nlm.nih.gov
The differential diagnosis of Parkinson's diseases (PD) is challenging, especially in the early
stages of the disease. We developed a microRNA profiling strategy for exosomal miRNAs …
stages of the disease. We developed a microRNA profiling strategy for exosomal miRNAs …
CircOGDH is a penumbra biomarker and therapeutic target in acute ischemic stroke
Y Liu, Y Li, J Zang, T Zhang, Y Li, Z Tan, D Ma… - Circulation …, 2022 - ahajournals.org
Background: Acute ischemic stroke (AIS) is a leading cause of disability and mortality
worldwide. Prediction of penumbra existence after AIS is crucial for making decision on …
worldwide. Prediction of penumbra existence after AIS is crucial for making decision on …
DIANA miRPath v. 2.0: investigating the combinatorial effect of microRNAs in pathways
MicroRNAs (miRNAs) are key regulators of diverse biological processes and their functional
analysis has been deemed central in many research pipelines. The new version of DIANA …
analysis has been deemed central in many research pipelines. The new version of DIANA …
Targeting the circulating microRNA signature of obesity
BACKGROUND Genomic studies have yielded important insights into the pathogenesis of
obesity. Circulating microRNAs (miRNAs) are valuable biomarkers of systemic diseases and …
obesity. Circulating microRNAs (miRNAs) are valuable biomarkers of systemic diseases and …
MicroRNA-374a activates Wnt/β-catenin signaling to promote breast cancer metastasis
Tumor metastasis involves a series of biological steps during which the tumor cells acquire
the ability to invade surrounding tissues and survive outside the original tumor site. During …
the ability to invade surrounding tissues and survive outside the original tumor site. During …
Muscle specific microRNAs are regulated by endurance exercise in human skeletal muscle
Muscle specific miRNAs, myomiRs, have been shown to control muscle development in vitro
and are differentially expressed at rest in diabetic skeletal muscle. Therefore, we …
and are differentially expressed at rest in diabetic skeletal muscle. Therefore, we …
miRSystem: an integrated system for characterizing enriched functions and pathways of microRNA targets
Background Many prediction tools for microRNA (miRNA) targets have been developed, but
inconsistent predictions were observed across multiple algorithms, which can make further …
inconsistent predictions were observed across multiple algorithms, which can make further …