Advancing human gut microbiota research by considering gut transit time

N Procházková, G Falony, LO Dragsted, TR Licht… - Gut, 2023 - gut.bmj.com
Accumulating evidence indicates that gut transit time is a key factor in sha** the gut
microbiota composition and activity, which are linked to human health. Both population-wide …

High-fat, western-style diet, systemic inflammation, and gut microbiota: a narrative review

IJ Malesza, M Malesza, J Walkowiak, N Mussin… - Cells, 2021 - mdpi.com
The gut microbiota is responsible for recovering energy from food, providing hosts with
vitamins, and providing a barrier function against exogenous pathogens. In addition, it is …

The gut microbiota contributes to the pathogenesis of anorexia nervosa in humans and mice

Y Fan, RK Støving, S Berreira Ibraim… - Nature …, 2023 - nature.com
Anorexia nervosa (AN) is an eating disorder with a high mortality. About 95% of cases are
women and it has a population prevalence of about 1%, but evidence-based treatment is …

Meta-analysis of fecal metagenomes reveals global microbial signatures that are specific for colorectal cancer

J Wirbel, PT Pyl, E Kartal, K Zych, A Kashani… - Nature medicine, 2019 - nature.com
Association studies have linked microbiome alterations with many human diseases.
However, they have not always reported consistent results, thereby necessitating cross …

Statin therapy is associated with lower prevalence of gut microbiota dysbiosis

S Vieira-Silva, G Falony, E Belda, T Nielsen… - Nature, 2020 - nature.com
Microbiome community ty** analyses have recently identified the Bacteroides 2 (Bact2)
enterotype, an intestinal microbiota configuration that is associated with systemic …

The neuroactive potential of the human gut microbiota in quality of life and depression

M Valles-Colomer, G Falony, Y Darzi… - Nature …, 2019 - nature.com
The relationship between gut microbial metabolism and mental health is one of the most
intriguing and controversial topics in microbiome research. Bidirectional microbiota–gut …

Microbial tryptophan catabolites in health and disease

HM Roager, TR Licht - Nature communications, 2018 - nature.com
Accumulating evidence implicates metabolites produced by gut microbes as crucial
mediators of diet-induced host-microbial cross-talk. Here, we review emerging data …

Cardiometabolic health, diet and the gut microbiome: a meta-omics perspective

M Valles-Colomer, C Menni, SE Berry, AM Valdes… - Nature Medicine, 2023 - nature.com
Cardiometabolic diseases have become a leading cause of morbidity and mortality globally.
They have been tightly linked to microbiome taxonomic and functional composition, with diet …

Effect of host genetics on the gut microbiome in 7,738 participants of the Dutch Microbiome Project

EA Lopera-Maya, A Kurilshikov, A van der Graaf, S Hu… - Nature …, 2022 - nature.com
Host genetics are known to influence the gut microbiome, yet their role remains poorly
understood. To robustly characterize these effects, we performed a genome-wide …

An online atlas of human plasma metabolite signatures of gut microbiome composition

KF Dekkers, S Sayols-Baixeras, G Baldanzi… - Nature …, 2022 - nature.com
Human gut microbiota produce a variety of molecules, some of which enter the bloodstream
and impact health. Conversely, dietary or pharmacological compounds may affect the …