Industrial applications of the Diels–Alder reaction

JA Funel, S Abele - Angewandte Chemie International Edition, 2013‏ - Wiley Online Library
Abstract The Diels–Alder reaction is one of the most popular transformations for organic
chemists to generate molecular complexity efficiently. Surprisingly, little is known about its …

Industrielle Anwendungen der Diels‐Alder‐Reaktion

JA Funel, S Abele - Angewandte Chemie, 2013‏ - Wiley Online Library
Abstract Die Diels‐Alder‐Reaktion ist eine der beliebtesten Reaktionen aus dem Repertoire
des Synthesechemikers zum effizienten Aufbau komplexer Moleküle. Überraschenderweise …

2-Substituted-1-naphthols as potent 5-lipoxygenase inhibitors with topical antiinflammatory activity

DG Batt, GD Maynard, JJ Petraitis… - Journal of medicinal …, 1990‏ - ACS Publications
The synthesis, biological evaluation, and structure-activity relationships of a series of 1-
naphthols bearingcarbon substituents at the 2-position are described. These compounds …

Biological study of naphthalene derivatives with antiinflammatory activities

MH Huang, SN Wu, JP Wang, CH Lin… - Drug development …, 2003‏ - Wiley Online Library
In this study, 18 synthetic naphthalene derivatives were tested for their inhibitory effects on
the activation of neutrophils stimulated with N‐formyl‐methionyl‐leucyl‐phenylalanine …

General regiospecific synthesis of annulated quinones

HW Moore, ST Perri - The Journal of Organic Chemistry, 1988‏ - ACS Publications
Reported here are the details of a general, convergent, regiospecific and high-yield
synthesis of annulated hy-droquinones and quiñones. 1, 2 It involves the thermal …

1 5-Lipoxygenase inhibitors and their anti-inflammatory activities

DG Batt - Progress in medicinal chemistry, 1992‏ - Elsevier
Publisher Summary This chapter elaborates about 5-Lipoxygenase inhibitors and their anti-
inflammatory activities. Oxidation of arachidonic acid in mammalian cells gives rise to a …

5-Lipoxygenase, leukotrienes biosynthesis and potential antileukotrienic agents

J Jampilek, M Dolezal, V Opletalova… - Current medicinal …, 2006‏ - benthamdirect.com
Leukotrienes play an important role in the inflammatory process accompanying allergic
diseases of respiratory, gastrointestinal and dermatological systems. Leukotrienes are …

Antipsoriatic anthrones with modulated redox properties. 1. Novel 10-substituted 1, 8-dihydroxy-9 (10H)-anthracenones as inhibitors of 5-lipoxygenase

K Müller, D Gürster, S Piwek… - Journal of medicinal …, 1993‏ - ACS Publications
The syntheses, the biological evaluation, and the structure-activity relationships of a novel
series of l, 8-dihydroxy-9 (10ff)-anthracenones bearing acyl-, alkyl-, or alkylidene-linked …

Antipsoriatic anthrones with modulated redox properties. 2. Novel derivatives of Chrysarobin and Isochrysarobin-antiproliferative activity and 5-lipoxygenase inhibition

K Mueller, P Leukel, K Ziereis… - Journal of medicinal …, 1994‏ - ACS Publications
A novel series of 2-and 3-substituted l, 8-dihydroxy-9 (10. H)-anthracenones were
synthesized and tested for their inhibitory activity against5-lipoxygenase (5-LO) in bovine …

Antipsoriatic anthrones with modulated redox properties. 4. Synthesis and biological activity of novel 9, 10-dihydro-1, 8-dihydroxy-9-oxo-2-anthracenecarboxylic and …

K Müller, H Prinz - Journal of medicinal chemistry, 1997‏ - ACS Publications
A novel series of carboxylic and hydroxamic acids based on 1, 8-dihydroxy-9 (10 H)-
anthracenone were synthesized from 8-hydroxy-1-methoxy-9, 10-anthracenedione as the …