Rolling circle amplification (RCA) enables the facile construction of compact and versatile
DNA nanoassemblies which are yet rarely explored for intracellular analysis. This is might …

The most commonly used clinical methods are enzyme-linked immunosorbent assay
(ELISA) and quantitative PCR (qPCR) in which ELISA was applied for the detection of …

The lateral flow immunoassay (LFIA) is a sought-after point-of-care testing platform, yet the
insufficient sensitivity of the LFIA limits its application in the detection of tumor biomarkers …

Exosomes are membrane-bound nanovesicles secreted by all cell types and contain diverse
molecules. Detecting cancer-derived exosomes and their cargo, which are closely related to …

Desirable biosensing assays need to be sensitive, specific, cost‐effective, instrument‐free,
and versatile. Herein we report a new strategy termed CLIPON (C RISPR and L arge DNA …

For point-of-care testing (POCT), coupling isothermal nucleic acid amplification schemes
(eg, recombinase polymerase amplification, RPA) with lateral flow assay (LFA) readout is an …

In this work, a tetrahedral DNA nanostructure (TDN) designed with multiple biomolecular
recognition domains (m-TDN) was assembled to construct an ultrasensitive electrochemical …

Foodborne pathogens pose a serious threat to human health worldwide. Combining
isothermal amplification techniques (eg, loop-mediated isothermal amplification, LAMP) with …

Portable point-of-care testing (POCT) is currently drawing enormous attention owing to its
great potential for disease diagnosis and personal health management. Electrochemical …

Constructing artificial domino nanoarchitectures, especially dynamic DNA circuits
associated with the actuation of biological functions inside live cells, represents a versatile …