Hypertension is available at http://hyper. ahajournals. org DOI: 10.1161/HYP.
0000000000000047 e8 Hypertension September 2016 distributed trait. Therefore, defining …

The establishment and maintenance of epithelial cell-cell junctions is crucially important to
regulate adhesion, apico-basal polarity and motility of epithelial cells, and ultimately controls …

The laboratory rat has been used for a long time as the model of choice in several
biomedical disciplines. Numerous inbred strains have been isolated, displaying a wide …

Rho kinase (ROCK) is a major downstream effector of the small GTPase RhoA. ROCK
family, consisting of ROCK1 and ROCK2, plays central roles in the organization of actin …

Cisplatin is a known antitumor drug, but its mechanisms of action are not fully elucidated. In
this research, we studied the anticancer potential of cisplatin at doses of 1, 2, or 3 μM using …

Background and Purpose—Obesity is an increasing epidemic worldwide; however, little is
known about effects of obesity produced by high-fat diet (HFD) on the cerebral circulation …

Podocytes play a critical role in maintaining glomerular permselectivity. It has been long
recognized that their intricate actin-based structures are tightly associated with their normal …

Population structure in genotype data has been extensively studied, and is revealed by
looking at the principal components of the genotype matrix. However, no similar analysis of …

Hypertension is one of the main adverse effects of antiangiogenic tumor drugs and thus
limits their application. The mechanism of hypertension caused by tyrosine kinase inhibitors …

The endothelin (ET) system has emerged as a therapeutic target for the treatment of diabetic
nephropathy (DN). The present study examined whether chronic endothelin A (ETA) …