Chemotherapy: a double-edged sword in cancer treatment

N Behranvand, F Nasri, R Zolfaghari Emameh… - Cancer immunology …, 2022 - Springer
Chemotherapy is a well-known and effective treatment for different cancers; unfortunately, it
has not been as efficient in the eradication of all cancer cells as been expected. The …

[HTML][HTML] Long non-coding RNAs: from disease code to drug role

Y Chen, Z Li, X Chen, S Zhang - Acta Pharmaceutica Sinica B, 2021 - Elsevier
Enormous studies have corroborated that long non-coding RNAs (lncRNAs) extensively
participate in crucial physiological processes such as metabolism and immunity, and are …

Natural compounds modulate the crosstalk between apoptosis-and autophagy-regulated signaling pathways: Controlling the uncontrolled expansion of tumor cells

C Braicu, O Zanoaga, AA Zimta, AB Tigu… - Seminars in Cancer …, 2022 - Elsevier
Due to the high number of annual cancer–related deaths, and the economic burden that this
malignancy affects today's society, the study of compounds isolated from natural sources …

Bioactive food compounds, epigenetics and chronic disease prevention: Focus on early-life interventions with polyphenols

LBAR Silva, N Pinheiro-Castro, GM Novaes… - Food Research …, 2019 - Elsevier
Consumption of bioactive compounds such as polyphenols, isothiocyanates, sulfur-
containing compounds and terpenoids, found in fruits and vegetables, is associated with …

Neuroprotective activity of green synthesized silver nanoparticles against methamphetamine-induced cell death in human neuroblastoma SH-SY5Y cells

S Khorrami, M Dogani, SE Mahani, MM Moghaddam… - Scientific Reports, 2023 - nature.com
The present study aimed to investigate the neuroprotective activity of the black peel
pomegranate extract, and silver nanoparticles (AgNPs) biosynthesized using the extract. We …

Role of Hedgehog and Hippo signaling pathways in cancer: a special focus on non-coding RNAs

U Sharma, HS Tuli, V Uttam, R Choudhary… - Pharmacological …, 2022 - Elsevier
Despite advanced clinical and translational oncology research, mortality rates are still
increasing worldwide. Recently, a class of non-coding RNAs (ncRNAs), such as microRNAs …

Flavonoids as epigenetic modulators for prostate cancer prevention

S Izzo, V Naponelli, S Bettuzzi - Nutrients, 2020 - mdpi.com
Prostate cancer (PCa) is a multifactorial disease with an unclear etiology. Due to its high
prevalence, long latency, and slow progression, PCa is an ideal target for chemoprevention …

[HTML][HTML] Quercetin regulates inflammation, oxidative stress, apoptosis, and mitochondrial structure and function in H9C2 cells by promoting PVT1 expression

F Li, J Liu, S Tang, J Yan, H Chen, D Li, X Yan - Acta Histochemica, 2021 - Elsevier
Objective To investigate the effect and potential mechanism of quercetin on inflammation,
oxidative stress, apoptosis, and mitochondrial structure and function in H9C2 cells. Materials …

[HTML][HTML] Regulation of main ncRNAs by polyphenols: A novel anticancer therapeutic approach

L Zhang, Q Kang, M Kang, S Jiang, F Yang, J Gong… - Phytomedicine, 2023 - Elsevier
Background Plant polyphenols have shown promising applications in oncotherapy.
Increasing evidence reveals that polyphenols possess the antitumor potential for multiple …

[HTML][HTML] Decoding LncRNAs

L Borkiewicz, J Kalafut, K Dudziak… - Cancers, 2021 - mdpi.com
Simple Summary Advances in RNA sequencing (RNA-seq) have led to the identification of
long non-coding RNAs (lncRNAs). Molecular studies on these molecules have shown that …