Background Clinical research affecting how doctors practice medicine is increasingly
sponsored by companies that make drugs and medical devices. Previous systematic …

There is considerable empirical support for the use of cognitive therapy in the treatment of
mild to moderately severe acute major depression. More recent research has focused on the …

Background Dose equivalence of antidepressants is critically important for clinical practice
and for research. There are several methods to define and calculate dose equivalence but …

Contrary to common belief, hypersexual or compulsive sexual behaviour disorder is not a
current fashion diagnosis. Nevertheless, the introduction of dedicated diagnostic guidelines …

Cancer patients could combine herbal treatments with their chemotherapy. We consulted
VigiBase, a WHO database of individual case safety reports (ICSRs) which archives reports …

Background There is emerging evidence that glutamatergic system dysfunction might play
an important role in the pathophysiology of bipolar depression. This review focuses on the …

Selective serotonin reuptake inhibitors (SSRIs) and serotonin and norepinephrine reuptake
inhibitors (SNRIs) show similar efficacy as treatments for anxiety, obsessive-compulsive, and …

Antidepressants are commonly prescribed medications in the United States, and there is
increasing interest in individualizing treatment selection for more than 20 US Food and Drug …

As a mental disease in modern society, depression shows an increasing occurrence, with
low cure rate and high recurrence rate. It has become the most disabling disease in the …

Depression is a common and heterogeneous condition with a chronic and recurrent natural
course that is frequently seen in the primary care setting. Primary care providers play a …