Acquired immunity to malaria

DL Doolan, C Dobaño, JK Baird - Clinical microbiology reviews, 2009 - Am Soc Microbiol
Naturally acquired immunity to falciparum malaria protects millions of people routinely
exposed to Plasmodium falciparum infection from severe disease and death. There is no …

Cerebral Plasmodium falciparum malaria: The role of PfEMP1 in its pathogenesis and immunity, and PfEMP1‐based vaccines to prevent it

AR Jensen, Y Adams, L Hviid - Immunological reviews, 2020 - Wiley Online Library
Malaria, a mosquito‐borne infectious disease caused by parasites of the genus Plasmodium
continues to be a major health problem worldwide. The unicellular Plasmodium‐parasites …

[HTML][HTML] Ancestry and pathology in King Tutankhamun's family

Z Hawass, YZ Gad, S Ismail, R Khairat, D Fathalla… - Jama, 2010 - jamanetwork.com
Context The New Kingdom in ancient Egypt, comprising the 18th, 19th, and 20th dynasties,
spanned the mid-16th to the early 11th centuries BC. The late 18th dynasty, which included …

PfEMP1–a parasite protein family of key importance in Plasmodium falciparum malaria immunity and pathogenesis

L Hviid, ATR Jensen - Advances in parasitology, 2015 - Elsevier
Plasmodium falciparum causes the most severe form of malaria and is responsible for
essentially all malaria-related deaths. The accumulation in various tissues of erythrocytes …

Malarial anemia: of mice and men

AA Lamikanra, D Brown, A Potocnik… - Blood, The Journal …, 2007 - ashpublications.org
Severe malaria is manifest by a variety of clinical syndromes dependent on properties of
both the host and the parasite. In young infants, severe malarial anemia (SMA) is the most …

Determination of the processes driving the acquisition of immunity to malaria using a mathematical transmission model

JAN Filipe, EM Riley, CJ Drakeley… - PLoS computational …, 2007 - journals.plos.org
Acquisition of partially protective immunity is a dominant feature of the epidemiology of
malaria among exposed individuals. The processes that determine the acquisition of …

[HTML][HTML] Interactions of malnutrition and immune impairment, with specific reference to immunity against parasites

S Hughes, P Kelly - Parasite immunology, 2006 - ncbi.nlm.nih.gov
It is well recognized that the relationship between malnutrition and infection is an intimate
one, and it is often assumed that this is because of impaired immune function. Management …

A mathematical model for the dynamics of malaria in a human host and mosquito vector with temporary immunity

J Tumwiine, JYT Mugisha, LS Luboobi - Applied mathematics and …, 2007 - Elsevier
In the paper, we propose a model that tracks the dynamics of malaria in the human host and
mosquito vector. Our model incorporates some infected humans that recover from infection …

[HTML][HTML] A novel domain cassette identifies Plasmodium falciparum PfEMP1 proteins binding ICAM-1 and is a target of cross-reactive, adhesion-inhibitory antibodies

A Bengtsson, L Joergensen, TS Rask… - The Journal of …, 2013 - journals.aai.org
Cerebral Plasmodium falciparum malaria is characterized by adhesion of infected
erythrocytes (IEs) to the cerebral microvasculature. This has been linked to parasites …

[HTML][HTML] Plasmodium falciparum infection and naturally acquired immunity to malaria antigens among Ghanaian children in Northern Ghana

Z Seidu, H Lamptey, M Lopez-Perez, NO Whittle… - Parasite epidemiology …, 2023 - Elsevier
Background The surge in malaria cases and deaths in recent years, particularly in Africa,
despite the widespread implementation of malaria-control measures could be due to …