Management of motion and anatomical variations in charged particle therapy: past, present, and into the future

JM Pakela, A Knopf, L Dong, A Rucinski… - Frontiers in …, 2022 - frontiersin.org
The major aim of radiation therapy is to provide curative or palliative treatment to cancerous
malignancies while minimizing damage to healthy tissues. Charged particle radiotherapy …

[HTML][HTML] Particle arc therapy: Status and potential

S Mein, S Wuyckens, X Li, S Both, A Carabe… - Radiotherapy and …, 2024 - Elsevier
There is a rising interest in develo** and utilizing arc delivery techniques with charged
particle beams, eg, proton, carbon or other ions, for clinical implementation. In this work …

Treatment planning in arc proton therapy: comparison of several optimization problem statements and their corresponding solvers

S Wuyckens, M Saint-Guillain, G Janssens… - Computers in biology …, 2022 - Elsevier
Arc proton therapy (ArcPT) is an emerging modality in cancer treatments. It delivers the
proton beams following a sequence of irradiation angles while the gantry is continuously …

Fast robust optimization of proton PBS arc therapy plans using early energy layer selection and spot assignment

E Engwall, C Battinelli, V Wase, O Marthin… - Physics in Medicine …, 2022 - iopscience.iop.org
Objective. Proton pencil-beam scanning arcs (PBS arcs) have gained much attention during
the past years, due to its potential for increased clinical benefit compared to conventional …

An overview of head and neck tumor reirradiation: What has been achieved so far?

K Gordon, D Smyk, I Gulidov, K Golubev, T Fatkhudinov - Cancers, 2023 - mdpi.com
Simple Summary Head and neck cancers are highly prevalent worldwide. Despite the recent
advances in cancer diagnosis and treatment, more than 50% of the cases relapse within 2 …

[HTML][HTML] FLASH instead of proton arc therapy is a more promising advancement for the next generation proton radiotherapy

M Kang, X Ding, Y Rong - Journal of applied clinical medical …, 2023 - ncbi.nlm.nih.gov
In the clinical practice of radiation oncology, we rely on precise dose calculation and
deposition, 1–3 high dose conformity 4–7 to the target while lowering the dose to the …

[HTML][HTML] Treatment planning comparison for head and neck cancer between photon, proton, and combined proton–photon therapy–From a fixed beam line to an arc

F Amstutz, R Krcek, B Bachtiary, DC Weber… - Radiotherapy and …, 2024 - Elsevier
Background and purpose This study investigates whether combined proton–photon therapy
(CPPT) improves treatment plan quality compared to single-modality intensity-modulated …

Biological and mechanical synergies to deal with proton therapy pitfalls: minibeams, FLASH, arcs, and gantryless rooms

A Mazal, JA Vera Sanchez… - Frontiers in …, 2021 - frontiersin.org
Proton therapy has advantages and pitfalls comparing with photon therapy in radiation
therapy. Among the limitations of protons in clinical practice we can selectively mention …

Dosimetric analysis of six whole-breast irradiation techniques in supine and prone positions

DW Kim, CS Hong, J Son, SY Kim, YI Park, M Chung… - Scientific Reports, 2024 - nature.com
In breast cancer radiation therapy, minimizing radiation-related risks and toxicity is vital for
improving life expectancy. Tailoring radiotherapy techniques and treatment positions can …

Lung stereotactic body radiotherapy (SBRT) using spot-scanning proton arc (SPArc) therapy: a feasibility study

G Liu, L Zhao, A Qin, I Grills, R Deraniyagala… - Frontiers in …, 2021 - frontiersin.org
Purpose We developed a 4D interplay effect model to quantitatively evaluate breathing-
induced interplay effects and assess the feasibility of utilizing spot-scanning proton arc …