[HTML][HTML] Myocarditis and inflammatory cardiomyopathy: current evidence and future directions

C Tschöpe, E Ammirati, B Bozkurt… - Nature Reviews …, 2021 - nature.com
Inflammatory cardiomyopathy, characterized by inflammatory cell infiltration into the
myocardium and a high risk of deteriorating cardiac function, has a heterogeneous …

Therapeutic strategies targeting inflammation and immunity in atherosclerosis: how to proceed?

SE Engelen, AJB Robinson, YX Zurke… - Nature Reviews …, 2022 - nature.com
Atherosclerosis is a chronic inflammatory disease of the arterial wall, characterized by the
formation of plaques containing lipid, connective tissue and immune cells in the intima of …

The role of inflammation in cardiovascular disease

MY Henein, S Vancheri, G Longo… - International journal of …, 2022 - mdpi.com
Atherosclerosis is a chronic inflammatory disease, in which the immune system has a
prominent role in its development and progression. Inflammation-induced endothelial …

The biological basis for cardiac repair after myocardial infarction: from inflammation to fibrosis

SD Prabhu, NG Frangogiannis - Circulation research, 2016 - Am Heart Assoc
In adult mammals, massive sudden loss of cardiomyocytes after infarction overwhelms the
limited regenerative capacity of the myocardium, resulting in the formation of a collagen …

Hepatic macrophages in liver homeostasis and diseases-diversity, plasticity and therapeutic opportunities

Y Wen, J Lambrecht, C Ju, F Tacke - Cellular & molecular immunology, 2021 - nature.com
Macrophages, which are key cellular components of the liver, have emerged as essential
players in the maintenance of hepatic homeostasis and in injury and repair processes in …

Macrophage plasticity and polarization: in vivo veritas

A Sica, A Mantovani - The Journal of clinical investigation, 2012 - Am Soc Clin Investig
Diversity and plasticity are hallmarks of cells of the monocyte-macrophage lineage. In
response to IFNs, Toll-like receptor engagement, or IL-4/IL-13 signaling, macrophages …

Protective and pathogenic functions of macrophage subsets

PJ Murray, TA Wynn - Nature reviews immunology, 2011 - nature.com
Macrophages are strategically located throughout the body tissues, where they ingest and
process foreign materials, dead cells and debris and recruit additional macrophages in …

From monocytes to M1/M2 macrophages: phenotypical vs. functional differentiation

P Italiani, D Boraschi - Frontiers in immunology, 2014 - frontiersin.org
Studies on monocyte and macrophage biology and differentiation have revealed the
pleiotropic activities of these cells. Macrophages are tissue sentinels that maintain tissue …

[HTML][HTML] Fate map** reveals origins and dynamics of monocytes and tissue macrophages under homeostasis

S Yona, KW Kim, Y Wolf, A Mildner, D Varol, M Breker… - Immunity, 2013 - cell.com
Mononuclear phagocytes, including monocytes, macrophages, and dendritic cells,
contribute to tissue integrity as well as to innate and adaptive immune defense. Emerging …

Developmental and functional heterogeneity of monocytes

M Guilliams, A Mildner, S Yona - Immunity, 2018 - cell.com
Novel experimental approaches such as fate-map** and single-cell analysis have brought
fresh insight into monocyte development and function over the past decade and helped …