The uniformity and stability of cellular mass density in mammalian cell culture
Cell dry mass is principally determined by the sum of biosynthesis and degradation.
Measurable change in dry mass occurs on a time scale of hours. By contrast, cell volume …
Measurable change in dry mass occurs on a time scale of hours. By contrast, cell volume …
Epithelial tissue confinement inhibits cell growth and leads to volume-reducing divisions
Cell proliferation is a central process in tissue development, homeostasis, and disease, yet
how proliferation is regulated in the tissue context remains poorly understood. Here, we …
how proliferation is regulated in the tissue context remains poorly understood. Here, we …
In situ quantification of osmotic pressure within living embryonic tissues
Mechanics is known to play a fundamental role in many cellular and developmental
processes. Beyond active forces and material properties, osmotic pressure is believed to …
processes. Beyond active forces and material properties, osmotic pressure is believed to …
Physiological stress drives the emergence of a Salmonella subpopulation through ribosomal RNA regulation
Bacteria undergo cycles of growth and starvation to which they must adapt swiftly. One
important strategy for adjusting growth rates relies on ribosomal levels. Although high …
important strategy for adjusting growth rates relies on ribosomal levels. Although high …
A Comparison of the Effects of Continuous Illumination and Day/Night Regimes on PHB Accumulation in Synechocystis Cells
C Fleischhacker-Daffert, A Zerobin, F Hummel… - Life, 2024 - pmc.ncbi.nlm.nih.gov
Poly (3-hydroxybutyrate)(PHB) is a biobased and biodegradable polymer with properties
comparable to polypropylene and therefore has the potential to replace conventional …
comparable to polypropylene and therefore has the potential to replace conventional …
Volume regulation in adhered cells: Roles of surface tension and cell swelling
The volume of adhered cells has been shown experimentally to decrease during spreading.
This effect can be understood from the pump-leak model, which we have extended to …
This effect can be understood from the pump-leak model, which we have extended to …
Stochastic Gene Expression Model of Nuclear-to-Cell Ratio Homeostasis
X Bai, TG Fai - arxiv preprint arxiv:2407.19066, 2024 - arxiv.org
Cell size varies between different cell types, and between different growth and osmotic
conditions. However, the nuclear-to-cell volume ratio (N/C ratio) remains nearly constant. In …
conditions. However, the nuclear-to-cell volume ratio (N/C ratio) remains nearly constant. In …
Mitosis sets nuclear homeostasis of cancer cells under confinement
M Mouelhi, A Saffon, M Roinard, H Delanoë-Ayari… - bioRxiv, 2023 - biorxiv.org
During their life, mammalian cells are subjected to numerous mechanical constraints,
especially in pathological contexts such as cancer. Recent studies have highlighted the …
especially in pathological contexts such as cancer. Recent studies have highlighted the …