Advances in copper complexes as anticancer agents

C Santini, M Pellei, V Gandin, M Porchia… - Chemical …, 2014 - ACS Publications
Medicinal inorganic chemistry offers additional opportunities for the design of therapeutic
agents not accessible to organic compounds. 1− 3 The wide range of coordination numbers …

Zinc complexes with nitrogen donor ligands as anticancer agents

M Porchia, M Pellei, F Del Bello, C Santini - Molecules, 2020 - mdpi.com
The search for anticancer metal-based drugs alternative to platinum derivatives could not
exclude zinc derivatives due to the importance of this metal for the correct functioning of the …

Mixed-ligand copper (II)-phenolate complexes: effect of coligand on enhanced DNA and protein binding, DNA cleavage, and anticancer activity

V Rajendiran, R Karthik, M Palaniandavar… - Inorganic …, 2007 - ACS Publications
The copper (II) complex [Cu (tdp)(ClO4)]· 0.5 H2O (1), where H (tdp) is the tetradentate
ligand 2-[(2-(2-hydroxyethylamino) ethylimino) methyl] phenol, and the mixed ligand …

Biomolecular interaction, anti-cancer and anti-angiogenic properties of cobalt (III) Schiff base complexes

S Ambika, Y Manojkumar, S Arunachalam… - Scientific reports, 2019 - nature.com
Two cobalt (III) Schiff base complexes, trans-[Co (salen)(DA) 2](ClO4)(1) and trans-[Co
(salophen)(DA) 2](ClO4)(2)(where salen: N, N'-bis (salicylidene) ethylenediamine, salopen …

Interactions of copper complexes with nucleic acids

A Erxleben - Coordination Chemistry Reviews, 2018 - Elsevier
Covalent or non-covalent interactions with DNA are the basis for many potential biomedical
applications of copper complexes, ranging from DNA structural probes and footprinting …

Synthesis, electronic structure, DNA and protein binding, DNA cleavage, and anticancer activity of fluorophore-labeled copper (II) complexes

SS Bhat, AA Kumbhar, H Heptullah, AA Khan… - Inorganic …, 2011 - ACS Publications
Two mononuclear fluorophore-labeled copper (II) complexes [Cu (nip)(acac)]+(2) and [Cu
(nip) 2] 2+(3), where fluorophore is 2-(naphthalen-1-yl)-1 H-imidazo [4, 5-f][1, 10] …

Mixed Ligand Copper(II) Complexes of N,N-Bis(benzimidazol-2-ylmethyl)amine (BBA) with Diimine Co-Ligands: Efficient Chemical Nuclease and Protease Activities …

R Loganathan, S Ramakrishnan, E Suresh… - Inorganic …, 2012 - ACS Publications
A series of mononuclear mixed ligand copper (II) complexes [Cu (bba)(diimine)](ClO4) 2 1–
4, where bba is N, N-bis (benzimidazol-2-ylmethyl) amine and diimine is 2, 2′-bipyridine …

Induction of Cell Death by Ternary Copper(II) Complexes of l-Tyrosine and Diimines: Role of Coligands on DNA Binding and Cleavage and Anticancer Activity

S Ramakrishnan, V Rajendiran… - Inorganic …, 2009 - ACS Publications
The mononuclear mixed ligand copper (II) complexes of the type [Cu (l-tyr)(diimine)](ClO4),
where tyr is l-tyrosine and diimine is 2, 2′-bipyridine (bpy)(1), 1, 10-phenanthroline …

Two new ternary complexes of copper (II) with tetracycline or doxycycline and 1, 10-phenanthroline and their potential as antitumoral: cytotoxicity and DNA cleavage

PP Silva, W Guerra, JN Silveira, AMC Ferreira… - Inorganic …, 2011 - ACS Publications
This paper reports on the synthesis and characterization of two new ternary copper (II)
complexes:[Cu (doxycycline)(1, 10-phenanthroline)(H2O)(ClO4)](ClO4)(1) and [Cu …

Toward the development of metal-based synthetic nucleases: DNA binding and oxidative DNA cleavage of a mixed copper (II) complex with N-(9H-purin-6-yl) …

JL García-Giménez, M González-Álvarez… - Journal of inorganic …, 2009 - Elsevier
The complex [Cu (N9-ABS)(phen) 2]· 3.6 H2O, H2N9-ABS= N-(9H-purin-6-yl)
benzenesulfonamide and phen= 1, 10-phenanthroline, has been synthesized and then …