Meningitis is defined as the inflammation of the meninges that is most often caused by
various bacterial and viral pathogens, and is associated with high rates of mortality and …

Acute community-acquired bacterial meningitis (BM) requires rapid diagnosis so that
suitable treatment can be instituted within 60 minutes of admitting the patient. The …

The differential diagnosis of acute community-acquired meningitis is of paramount
importance in both therapeutic and healthcare-related economic terms. Despite the routinely …

Background: Metastatic spread into the cerebrospinal fluid (CSF) represents a severe
complication of malignant disease with poor prognosis. Although early diagnosis is crucial …

Purpose There is an overlap in the cerebrospinal fluid (CSF) characteristics of patients
presenting with different etiologies of CSF pleocytosis. Here, we characterized patients with …

Background Lipopolysaccharide (LPS) is one of the main constituents of the cell wall of
gram-negative bacteria. As an endotoxin, LPS induces neuroinflammation, which is …

Objective To review the current literature pertaining to the use of lactate as a prognostic
indicator and therapeutic guide, the utility of measuring lactate concentrations in body fluids …

B. Hoen a, 1, E. Varon b, 1, T. de Debroucker c, 1, B. Fantin d, 1, E. Grimprel e, 1, M. Wolff f,
1, X. Duval g,∗, the expert and reviewing group a Maladies Infectieuses, CHU de …

Infections of the nervous system are an important and challenging aspect of clinical
neurology. Immediate correct diagnosis enables to introduce effective therapy, in conditions …

Differential diagnosis between bacterial and viral meningitis is crucial. In our study, to
differentiate bacterial vs. viral meningitis, three machine learning (ML) algorithms (multiple …