Global epidemiology of rheumatoid arthritis

A Finckh, B Gilbert, B Hodkinson, SC Bae… - Nature Reviews …, 2022 - nature.com
Rheumatoid arthritis (RA) is a systemic autoimmune disease that predominantly affects the
joints. The prevalence of RA varies globally, with generally a higher prevalence in …

Mechanisms of action of hydroxychloroquine and chloroquine: implications for rheumatology

E Schrezenmeier, T Dörner - Nature Reviews Rheumatology, 2020 - nature.com
Despite widespread clinical use of antimalarial drugs such as hydroxychloroquine and
chloroquine in the treatment of rheumatoid arthritis (RA), systemic lupus erythematosus …

Cardiovascular risk in inflammatory arthritis: rheumatoid arthritis and gout

R Hansildaar, D Vedder, M Baniaamam… - The Lancet …, 2021 - thelancet.com
The increased risk of cardiovascular morbidity and mortality in rheumatoid arthritis and gout
has been increasingly acknowledged in past decades, with accumulating evidence that …

A population-based cohort study of rheumatoid arthritis-associated interstitial lung disease: comorbidity and mortality

C Hyldgaard, O Hilberg, AB Pedersen… - Annals of the rheumatic …, 2017 - Elsevier
Objectives To compare mortality risks in patients with rheumatoid arthritis-associated
interstitial lung disease (RA-ILD) and patients with RA without ILD. Design Matched cohort …

Filgotinib in combination with methotrexate or as monotherapy versus methotrexate monotherapy in patients with active rheumatoid arthritis and limited or no prior …

R Westhovens, WFC Rigby, D van der Heijde… - Annals of the rheumatic …, 2021 - Elsevier
Objectives To investigate efficacy and safety of the Janus kinase-1 inhibitor filgotinib in
patients with active rheumatoid arthritis (RA) with limited or no prior methotrexate (MTX) …

Cardiovascular co-morbidity in patients with rheumatoid arthritis: a narrative review of risk factors, cardiovascular risk assessment and treatment

A Jagpal, I Navarro-Millán - BMC rheumatology, 2018 - Springer
Cardiovascular disease (CVD) is markedly increased in patients with rheumatoid arthritis
partly due to accelerated atherosclerosis from chronic inflammation. Traditional …

Integrated safety analysis of filgotinib in patients with moderately to severely active rheumatoid arthritis receiving treatment over a median of 1.6 years

KL Winthrop, Y Tanaka, T Takeuchi, A Kivitz… - Annals of the rheumatic …, 2022 - Elsevier
Objective To characterise safety of the Janus kinase-1 preferential inhibitor filgotinib in
patients with moderately to severely active rheumatoid arthritis. Methods Data were …

Microvascular endothelial dysfunction in rheumatoid arthritis

R Bordy, P Totoson, C Prati, C Marie… - Nature Reviews …, 2018 - nature.com
The systemic autoimmune disease rheumatoid arthritis (RA) is characterized by increased
cardiovascular mortality and morbidity and is an independent cardiovascular risk factor …

Epidemiology and risk factors for rheumatoid arthritis development

AI Venetsanopoulou, Y Alamanos… - Mediterranean …, 2023 - pmc.ncbi.nlm.nih.gov
Rheumatoid arthritis (RA) is a prevalent chronic inflammatory arthritis worldwide,
significantly impacting patients and population health. The disease affects women primarily …

Autoimmunity and inflammation link to cardiovascular disease risk in rheumatoid arthritis

DJ DeMizio, LB Geraldino-Pardilla - Rheumatology and therapy, 2020 - Springer
Rheumatoid arthritis (RA) patients have a 50% increased risk of cardiovascular (CV)-related
morbidity and mortality. This excess CV risk is closely linked to RA disease severity and …