Skeletal muscle extracellular matrix–what do we know about its composition, regulation, and physiological roles? A narrative review
Skeletal muscle represents the largest body-composition component in humans. In addition
to its primary function in the maintenance of upright posture and the production of …
to its primary function in the maintenance of upright posture and the production of …
Hallmarks of ageing in human skeletal muscle and implications for understanding the pathophysiology of sarcopenia in women and men
Ageing is a complex biological process associated with increased morbidity and mortality.
Nine classic, interdependent hallmarks of ageing have been proposed involving genetic and …
Nine classic, interdependent hallmarks of ageing have been proposed involving genetic and …
Senescence atlas reveals an aged-like inflamed niche that blunts muscle regeneration
Tissue regeneration requires coordination between resident stem cells and local niche
cells,. Here we identify that senescent cells are integral components of the skeletal muscle …
cells,. Here we identify that senescent cells are integral components of the skeletal muscle …
Geriatric muscle stem cells switch reversible quiescence into senescence
P Sousa-Victor, S Gutarra, L García-Prat… - Nature, 2014 - nature.com
Regeneration of skeletal muscle depends on a population of adult stem cells (satellite cells)
that remain quiescent throughout life. Satellite cell regenerative functions decline with …
that remain quiescent throughout life. Satellite cell regenerative functions decline with …
Basic components of connective tissues and extracellular matrix: elastin, fibrillin, fibulins, fibrinogen, fibronectin, laminin, tenascins and thrombospondins
Collagens are the most abundant components of the extracellular matrix and many types of
soft tissues. Elastin is another major component of certain soft tissues, such as arterial walls …
soft tissues. Elastin is another major component of certain soft tissues, such as arterial walls …
Structure and function of the skeletal muscle extracellular matrix
AR Gillies, RL Lieber - Muscle & nerve, 2011 - Wiley Online Library
The skeletal muscle extracellular matrix (ECM) plays an important role in muscle fiber force
transmission, maintenance, and repair. In both injured and diseased states, ECM adapts …
transmission, maintenance, and repair. In both injured and diseased states, ECM adapts …
Aberrant repair and fibrosis development in skeletal muscle
The repair process of damaged tissue involves the coordinated activities of several cell
types in response to local and systemic signals. Following acute tissue injury, infiltrating …
types in response to local and systemic signals. Following acute tissue injury, infiltrating …
Platelet-rich plasma in orthopaedic applications: evidence-based recommendations for treatment
Autologous platelet-rich plasma (PRP) therapies have seen a dramatic increase in breadth
and frequency of use for orthopaedic conditions in the past 5 years. Rich in many growth …
and frequency of use for orthopaedic conditions in the past 5 years. Rich in many growth …
Basic components of connective tissues and extracellular matrix: fibronectin, fibrinogen, laminin, elastin, fibrillins, fibulins, matrilins, tenascins and thrombospondins
J Halper - Progress in heritable soft connective tissue diseases, 2021 - Springer
Collagens are the most abundant components of the extracellular matrix (ECM) and many
types of soft tissues. Elastin is another major component of certain soft tissues, such as …
types of soft tissues. Elastin is another major component of certain soft tissues, such as …
Alignment, cross linking, and beyond: a collagen architect's guide to the skeletal muscle extracellular matrix
RP Wohlgemuth, SE Brashear… - American Journal of …, 2023 - journals.physiology.org
The muscle extracellular matrix (ECM) forms a complex network of collagens, proteoglycans,
and other proteins that produce a favorable environment for muscle regeneration, protect the …
and other proteins that produce a favorable environment for muscle regeneration, protect the …