Validating immunohistochemistry assay specificity in investigative studies: considerations for a weight of evidence approach

JD Webster, M Solon… - Veterinary …, 2021 - journals.sagepub.com
Immunohistochemistry (IHC) is a fundamental molecular technique that provides information
on protein expression in the context of spatial localization and tissue morphology. IHC is …

Mitotic activity: A systematic literature review of the assessment methodology and prognostic value in canine tumors

CA Bertram, TA Donovan, A Bartel - Veterinary pathology, 2024 - journals.sagepub.com
One of the most relevant prognostic indices for tumors is cellular proliferation, which is most
commonly measured by the mitotic activity in routine tumor sections. The goal of this …

Equine genital squamous cell carcinoma associated with EcPV2 infection: RANKL pathway correlated to inflammation and Wnt signaling activation

S Mecocci, I Porcellato, F Armando, L Mechelli… - Biology, 2021 - mdpi.com
Simple Summary Equine genital squamous cell carcinomas (egSCCs) associated with
papilloma virus (PV) infection have been recently proposed as model for human PV-induced …

Immunohistochemical identification of T and B lymphocytes in formalin-fixed, paraffin-embedded tissues of 53 avian species using commercial antibodies

A Kurokawa, Y Yamamoto - Journal of Veterinary Medical Science, 2023 - jstage.jst.go.jp
Providing a method to detect avian lymphocytes by immunohistochemistry (IHC) would be
helpful for analyzing immune function and diagnosing diseases in birds. In this study, we …

Colonic T-cell–rich, large B-cell lymphoma associated with equid herpesvirus 5 infection and secondary trans-colonic fistula in a horse

HD Acevedo, AM Hassebroek… - Journal of …, 2023 - journals.sagepub.com
A 17-y-old Rocky Mountain gelding was presented to the Virginia-Maryland Veterinary
Teaching Hospital because of a 4-wk history of anorexia, weight loss, lethargy, and fever of …

Lymphoma & Myeloproliferative Disease

A Samuels, TA Burns - Veterinary Clinics: Equine Practice, 2024 - vetequine.theclinics.com
Alimentary lymphoma often causes chronic clinical signs: diarrhea, weight loss, and
intermittent colic. Research in companion animals suggests that alimentary lymphoma may …

Systematic Review of Methods and Prognostic Value of Mitotic Activity. Part 2: Canine Tumors

CA Bertram, TA Donovan, A Bartel - arxiv preprint arxiv:2305.19667, 2023 - arxiv.org
One of the most relevant prognostication tests for tumors is cellular proliferation, which is
most commonly measured by the mitotic activity in routine tumor sections. The goal of this …

Equine Gastrointestinal Neoplasia

I Mersich, PA Wilkins - Veterinary Clinics: Equine Practice, 2024 - vetequine.theclinics.com
Gastrointestinal neoplasia is rare in equine patients. 1 Most commonly found tumors of the
equine gastrointestinal tract are alimentary lymphoma, intestinal adenocarcinoma, intestinal …

Multicentric lymphoma in a donkey with intestinal and bone marrow involvement

G Paraschou, C Xue, R Egan, P Bolfa - BMC veterinary research, 2024 - Springer
Background Lymphoma is a common neoplasm in horses but is reported much less
commonly in donkeys. In this case report, we describe the macroscopic, microscopic and …

Nodular hyperplasia of lymphoglandular complexes in dogs: A potential diagnostic pitfall for rectal masses

AW Stent, M Kiupel, JRS Dandrieux… - Veterinary …, 2024 - journals.sagepub.com
Lymphoglandular complexes are components of the gut-associated lymphoid tissue that are
characterized by submucosal lymphoid aggregates invested by projections of mucosal …