Graft failure after allogeneic hematopoietic stem cell transplantation

ZN Ozdemir, SC Bozdağ - Transfusion and apheresis science, 2018 - Elsevier
Graft failure is a serious complication of allogeneic hematopoietic stem cell transplantation
(allo-HSCT) defined as either lack of initial engraftment of donor cells (primary graft failure) …

[HTML][HTML] Graft failure after allogeneic hematopoietic cell transplantation

J Mattsson, O Ringdén, R Storb - Biology of blood and marrow …, 2008 - Elsevier
Graft failure is a significant complication following allogeneic hematopoietic cell
transplantation (alloHCT). It may result from rejection caused by recipient T cells, natural …

Activation of PPARδ in bone marrow endothelial progenitor cells improves their hematopoiesis-supporting ability after myelosuppressive injury

M Liang, ZS Lyu, YY Zhang, SQ Tang, T **ng, YH Chen… - Cancer Letters, 2024 - Elsevier
Dysfunctional bone marrow (BM) endothelial progenitor cells (EPCs) with high levels of
reactive oxygen species (ROS) are responsible for defective hematopoiesis in poor graft …

Single-cell dissection of human hematopoietic reconstitution after allogeneic hematopoietic stem cell transplantation

Y Huo, L Wu, A Pang, Q Li, F Hong, C Zhu, Z Yang… - Science …, 2023 - science.org
Hematopoietic stem cell transplantation is an effective regenerative therapy for many
malignant, inherited, or autoimmune diseases. However, our understanding of reconstituted …

Clinical features, pathophysiology, and therapy of poor graft function post–allogeneic stem cell transplantation

A Prabahran, R Koldej, L Chee, D Ritchie - Blood Advances, 2022 - ashpublications.org
Poor graft function (PGF), defined by the presence of multilineage cytopenias in the
presence of 100% donor chimerism, is a serious complication of allogeneic stem cell …

[HTML][HTML] Association of an impaired bone marrow microenvironment with secondary poor graft function after allogeneic hematopoietic stem cell transplantation

Y Kong, YJ Chang, YZ Wang, YH Chen, W Han… - Biology of blood and …, 2013 - Elsevier
Poor graft function (PGF) is a serious complication after allogeneic hematopoietic stem cell
transplantation (allo-HSCT). Whether abnormalities of the bone marrow (BM) …

[HTML][HTML] Incidence, risk factors, and outcomes of primary poor graft function after allogeneic hematopoietic stem cell transplantation

Y Zhao, F Gao, J Shi, Y Luo, Y Tan, X Lai, J Yu… - Biology of Blood and …, 2019 - Elsevier
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a curative therapy for both
malignant and nonmalignant hematologic disorders. However, primary poor graft function …

Atorvastatin enhances endothelial cell function in posttransplant poor graft function

MM Shi, Y Kong, Y Song, YQ Sun… - Blood, The Journal …, 2016 - ashpublications.org
Poor graft function (PGF) is a serious complication after allogeneic hematopoietic stem cell
transplantation (allo-HSCT). Murine studies suggest that endothelial progenitor cells (EPCs) …

Current and future approaches to treat graft failure after allogeneic hematopoietic stem cell transplantation

F Locatelli, B Lucarelli, P Merli - Expert opinion on …, 2014 - Taylor & Francis
Introduction: One significant obstacle to the success of allogeneic hematopoietic stem cell
transplantation (HSCT) is represented by graft failure, defined as either lack of initial …

Immunological basis of bone marrow failure after allogeneic hematopoietic stem cell transplantation

S Masouridi-Levrat, F Simonetta… - Frontiers in …, 2016 - frontiersin.org
Bone marrow failure (BMF) syndromes are severe complications of allogeneic
hematopoietic stem cell transplantation (allo-HSCT). In this paper, we distinguish two …