Recently, multifunctional drug delivery systems (DDSs) have been designed to provide a
comprehensive approach with multiple functionalities, including diagnostic imaging …

Background In recent years, the field of nanotechnology and nanomedicine has transformed
the pharmaceutical industry with the development of novel drug delivery systems that …

Cilostazol (CLZ) is an antiplatelet agent with limited solubility (∼ 6 μg/ml at 25° C), poor
absorption and low oral bioavailability. In this study, solid lipid nanoparticles (SLNs) were …

The blood-brain barrier (BBB) and the blood-cerebrospinal fluid barrier (BCSF) are two of
the most complex and sophisticated concierges that defend the central nervous system …

Polyphenol is contained in a plant as a secondary metabolite product. It potentially has
benefits for the body but quickly has unstable characteristics due to temperature, pH, etc …

Catechol-O-methyltransferase inhibitors (iCOMT), such as entacapone, have been
successfully employed to treat tremor-related symptoms of Parkinson's disease. However …

Lung cancer is a complex thoracic malignancy develo** consequential to aberrations in a
myriad of molecular and biomolecular signaling pathways. It is one of the most lethal forms …

Lipid-based nanoparticles are one of the most promising encapsulation technologies in the
field of nanotechnology, and solid lipid nanoparticles were the first generation of such …

High-pressure homogenization (HPH) has been employed for unit operations like
comminution, mixing, and stabilization of pharmaceutical solids and nanoparticles. With …

Chronic wounds are a remarkable cause of morbidity, requiring long-time treatments with a
significant impact on the quality of life and high costs for public health. Although there are a …