Benzodiazepines (BZDs), a diverse class of benzofused seven-membered N-heterocycles,
display essential pharmacological properties and play vital roles in some biochemical …

Isocyanide-based multicomponent reactions in the synthesis of heterocycles - RSC Advances
(RSC Publishing) DOI:10.1039/C6RA02143C Royal Society of Chemistry View PDF …

In addition to isocyanide-based Ugi, Passerini, van Leusen, and Orru multicomponent
reactions (IMCRs), a new class of isocyanide/acetylene-based multicomponent reactions …

The last decade has seen a tremendous outburst in modifying chemical processes to make
them 'green'or at least acceptable so as to attain sustainability of our environment. People …

The role of tritylamine is introduced as a convenient ammonia substitute in the Ugi tetrazole
synthesis. Fifteen examples and their mild cleavage products are described in satisfactory to …

Multicomponent reactions, which lead to synthesis of target compounds with inherent
molecular diversity, greater efficiency and atom economy, are single step types of reactions …

Abstract A series of novel 1, 5-benzodiazepine-2, 4-dione derivatives with C-6 amide
substituents were designed and synthesized using three-component reactions. The …

Benzodiazepinones are an important family of heterocycles with very attractive
pharmacological properties and peptidomimetic abilities. We report herein a rapid and …

An efficient method has been developed for the synthesis of new pyrano [3, 2-c] and pyrano
[3, 2-a] carbazole derivatives via a three-component reaction of 4-hydroxycarbazole or 2 …

An efficient one‐pot four‐component protocol for the synthesis of imidazo [1, 2‐a] pyridines
was developed by condensing ethane‐1, 2‐diamine (2), 1, 1‐bis (methylthio)‐2‐nitroethene …