In their seminal 1983 paper, Gans and Northcutt proposed that evolution of the vertebrate
'new head'was made possible by the advent of the neural crest and cranial placodes. The …

Neural crest cells are a transient embryonic cell population that migrate collectively to
various locations throughout the embryo to contribute a number of cell types to several …

Our understanding of the cellular mechanisms governing carcinoma invasiveness and
metastasis has evolved dramatically over the last several years. The previous emphasis on …

The genetic basis of human facial variation and craniofacial birth defects remains poorly
understood. Distant-acting transcriptional enhancers control the fine-tuned spatiotemporal …

Summary The developmental disorder Floating-Harbor syndrome (FHS) is caused by
heterozygous truncating mutations in SRCAP, a gene encoding a chromatin remodeler …

Neural crest (NC) cells migrate throughout vertebrate embryos to give rise to a huge variety
of cell types, but when and where lineages emerge and their regulation remain unclear. We …

The chicken continues to hold its position as a leading model organism within many areas of
research, as well as being a major source of protein for human consumption. The First …

The neural crest is a migratory population of stem-like cells that contribute to multiple traits
including the bones of the skull, peripheral nervous system, and pigment. How neural crest …

Neural crest cells are a multipotent embryonic stem cell population that migrate large
distances to contribute a variety of tissues. The cranial neural crest, which contribute to …

Receptor tyrosine kinase-mediated growth factor signaling is essential for proper formation
and development of the neural crest. The many ligands and receptors implicated in these …