Exploiting quorum sensing to confuse bacterial pathogens
Cell-cell communication, or quorum sensing, is a widespread phenomenon in bacteria that
is used to coordinate gene expression among local populations. Its use by bacterial …
is used to coordinate gene expression among local populations. Its use by bacterial …
The paraoxonases: role in human diseases and methodological difficulties in measurement
Research into the paraoxonase (PON) gene family has flourished over the past few years. In
the 1970s and 1980s, only PON1 was known, and the investigations were conducted …
the 1970s and 1980s, only PON1 was known, and the investigations were conducted …
Antioxidants in the fight against atherosclerosis: is this a dead end?
Abstract Purpose of Review The purpose of this review is to focus on the outcome of recent
antioxidant interventions using synthetic and naturally occurring molecules established as …
antioxidant interventions using synthetic and naturally occurring molecules established as …
Paraoxonases as potential antibiofilm agents: their relationship with quorum-sensing signals in Gram-negative bacteria
The property of many bacteria to form biofilms constitutes a major health problem. Bacteria
living in biofilms have a very high resistance to antibiotics. Biofilms may develop at a certain …
living in biofilms have a very high resistance to antibiotics. Biofilms may develop at a certain …
Effects of pomegranate extract supplementation on cardiovascular risk factors and physical function in hemodialysis patients
The purpose of this study was to evaluate the effects of oral supplementation with
pomegranate extract on cardiovascular risk, physical function, oxidative stress, and …
pomegranate extract on cardiovascular risk, physical function, oxidative stress, and …
Purified human paraoxonase-1 interacts with plasma membrane lipid rafts and mediates cholesterol efflux from macrophages
Paraoxonase-1 (PON1) is a high-density lipoprotein (HDL)-associated serum enzyme
thought to make a major contribution to the antioxidant and anti-inflammatory capacities of …
thought to make a major contribution to the antioxidant and anti-inflammatory capacities of …
Syntheses and biological activities of chroman-2-ones. A review
Chroman-2-one (1), also referred to as dihydrocoumarin, and its derivatives have attracted
the attention of chemists due to their broad range of properties. Dihydrocoumarin contains a …
the attention of chemists due to their broad range of properties. Dihydrocoumarin contains a …
PPARs in regulation of paraoxonases: control of oxidative stress and inflammation pathways
The paraoxonase (PON) group of enzymes, composed of PON1, PON2, and PON3, play an
important role in decreasing oxidative stress by degrading lipid peroxides. PON1 synthesis …
important role in decreasing oxidative stress by degrading lipid peroxides. PON1 synthesis …
BpiB05, a novel metagenome-derived hydrolase acting on N-acylhomoserine lactones
P Bijtenhoorn, C Schipper, C Hornung… - Journal of …, 2011 - Elsevier
The N-acyl-homoserine lactones (N-AHLs) play an important role in bacterial cell–cell
signaling. Up to date, however, only a few different experimentally proven classes of N-AHL …
signaling. Up to date, however, only a few different experimentally proven classes of N-AHL …
Paraoxonase 1 interactions with HDL, antioxidants and macrophages regulate atherogenesis–a protective role for HDL phospholipids
M Efrat, M Aviram - Paraoxonases in Inflammation, Infection, and …, 2010 - Springer
Macrophage cholesterol accumulation and foam cell formation is the hallmark of early
atherogenesis. In addition to macrophages, at least three more major players regulate …
atherogenesis. In addition to macrophages, at least three more major players regulate …