Hijackers, hitchhikers, or co-drivers? The mysteries of mobilizable genetic elements

M Ares-Arroyo, C Coluzzi, JA Moura de Sousa… - PLoS …, 2024 - journals.plos.org
Mobile genetic elements shape microbial gene repertoires and populations. Recent results
reveal that many, possibly most, microbial mobile genetic elements require helpers to …

ICEberg 2.0: an updated database of bacterial integrative and conjugative elements

M Liu, X Li, Y **e, D Bi, J Sun, J Li, C Tai… - Nucleic acids …, 2019 - academic.oup.com
Abstract ICEberg 2.0 (http://db-mml. sjtu. edu. cn/ICEberg/) is an updated database that
provides comprehensive information about bacterial integrative and conjugative elements …

Evolution of plasmid mobility: origin and fate of conjugative and nonconjugative plasmids

C Coluzzi, MP Garcillán-Barcia… - Molecular Biology …, 2022 - academic.oup.com
Conjugation drives the horizontal transfer of adaptive traits across prokaryotes. One-fourth of
the plasmids encode the functions necessary to conjugate autonomously, the others being …

MOBscan: automated annotation of MOB relaxases

MP Garcillán-Barcia, S Redondo-Salvo… - Horizontal gene transfer …, 2020 - Springer
Relaxase-based plasmid classification has become popular in the past 10 years.
Nevertheless, it is not obvious how to assign a query protein to a relaxase MOB family …

Conjugative transfer of streptococcal prophages harboring antibiotic resistance and virulence genes

J Huang, X Dai, Z Wu, X Hu, J Sun, Y Tang… - The ISME …, 2023 - academic.oup.com
Prophages play important roles in the transduction of various functional traits, including
virulence factors, but remain debatable in harboring and transmitting antimicrobial …

Identifying conjugative plasmids and integrative conjugative elements with CONJscan

J Cury, SS Abby, O Doppelt-Azeroual, B Néron… - … Gene Transfer: Methods …, 2020 - Springer
We present a computational method to identify conjugative systems in plasmids and
chromosomes using the CONJscan module of MacSyFinder. The method relies on the …

ICEscreen: a tool to detect Firmicute ICEs and IMEs, isolated or enclosed in composite structures

J Lao, T Lacroix, G Guédon, C Coluzzi… - NAR Genomics and …, 2022 - academic.oup.com
Abstract Mobile Genetic Elements (MGEs) are integrated in bacterial genomes and key
elements that drive prokaryote genome evolution. Among them are Integrative and …

Lactic acid bacteria and bifidobacteria deliberately introduced into the agro-food chain do not significantly increase the antimicrobial resistance gene pool

V Rozman, P Mohar Lorbeg, P Treven, T Accetto… - Gut …, 2022 - Taylor & Francis
Lactic acid bacteria (LAB) and bifidobacteria may serve as reservoirs of antimicrobial
resistance, but the risk posed by strains intentionally introduced into the agro-food chain has …

Multilayer networks of plasmid genetic similarity reveal potential pathways of gene transmission

JT Shapiro, A Zorea, AB Kav, VJ Ontiveros… - The ISME …, 2023 - academic.oup.com
Antimicrobial resistance (AMR) is a significant threat to public health. Plasmids are principal
vectors of AMR genes, significantly contributing to their spread and mobility across hosts …